Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CFD | P00746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11900328 | 0.85 | HDAC6 (0.87) | HDAC6HDAC2HDAC8ALDH1A1GAA | |
| SCHEMBL10294849 | 0.85 | HDAC8 (0.62) | HDAC6HDAC2HDAC8MAPK1LMNA | |
| SCHEMBL16598155 | 0.85 | HDAC6 (0.66) | HDAC6HDAC2HDAC8MAPK1LMNA | |
| SCHEMBL27952268 | 0.85 | LMNA (0.70) | HDAC6HDAC2HDAC8MAPK1LMNA | |
| SCHEMBL22047184 | 0.82 | PPARG (0.78) | HDAC6HDAC2HDAC8LMNAALDH1A1 | |
| SCHEMBL10084687 | 0.81 | NPC1 (0.73) | HDAC6HDAC2HDAC8MAPK1LMNA | |
| SCHEMBL14044800 | 0.81 | HDAC2 (0.69) | HDAC6HDAC2HDAC8ALDH1A1GAA | |
| SCHEMBL13702290 | 0.81 | HDAC6 (0.74) | HDAC6HDAC2HDAC8ALDH1A1GAA | |
| SCHEMBL20095441 | 0.81 | SMN1; SMN2 (0.51) | LMNAALDH1A1GAAHSD17B10KMT2A | |
| SCHEMBL7803055 | 0.80 | KDR (0.58) | HDAC6HDAC2HDAC8MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010144359-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | ABRAXIS BIOSCIENCE, LLC (US) | 2010-12-16 | — | — | WO | disclosed |