Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002618 | 0.78 | TSHR (0.41) | KMOUNGALDH1A1KDM4EPOLB | |
| SCHEMBL8287817 | 0.78 | FFAR1 (0.39) | — | |
| SCHEMBL13002193 | 0.76 | PIK3CG (0.54) | MEN1KMT2ATDP1CA2RAB9A | |
| SCHEMBL13002386 | 0.76 | GAA (0.41) | ALDH1A1L3MBTL1KDM4EPOLBMEN1 | |
| SCHEMBL13002190 | 0.75 | KMO (0.34) | KMOPARP1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4274420 | 0.74 | PARP1 (0.72) | KMOUNGPARP1ALDH1A1KDM4E | |
| SCHEMBL13657995 | 0.72 | RXRA (0.42) | KMOPARP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5836928 | 0.70 | KMO (0.49) | KMOUNGPARP1ALDH1A1L3MBTL1 | |
| SCHEMBL4079910 | 0.68 | PARP1 (0.58) | KMOUNGPARP1ALDH1A1KDM4E | |
| Phenol SCHEMBL28650467 | 0.68 | PARP1 (0.62) | KMOPARP1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148351-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |