Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376524 | 0.83 | KDM1A (0.37) | KMT2AMEN1RAB9APOLBNPSR1 | |
| SCHEMBL3044688 | 0.82 | AKT1 (0.40) | KMT2ABCHEMEN1L3MBTL1 | |
| SCHEMBL29992652 | 0.82 | AKT1 (0.40) | KMT2ABCHEMEN1L3MBTL1 | |
| SCHEMBL13003012 | 0.78 | BCHE (0.45) | KMT2AALOX15F2BCHEEGFR | |
| SCHEMBL18714661 | 0.78 | BCHE (0.45) | KMT2AALOX15F2BCHEEGFR | |
| SCHEMBL7025500 | 0.77 | BCHE (0.42) | KMT2AALOX15F2BCHEEGFR | |
| SCHEMBL13003011 | 0.77 | NR5A1 (0.41) | KMT2AALOX15F2BCHEEGFR | |
| SCHEMBL3874926 | 0.73 | ALDH1A1 (0.45) | KMT2AMEN1TSHRPPARGPOLB | |
| SCHEMBL4418839 | 0.71 | PREP (0.34) | — | |
| SCHEMBL5635573 | 0.71 | NOTUM (0.53) | KMT2AALOX15F2BCHEEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757585-B1 | Anionically substituted 7-Nitroindoline derivatives and their uses | MEDICAL RES COUNCIL (GB) | 2010-12-01 | — | — | EP | disclosed |
| EP-1757585-A1 | Anionically substituted 7-Nitroindoline derivatives and their uses | Medical Research Council (GB) | 2007-02-28 | — | — | EP | disclosed |