Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118407 | 0.87 | CA12 (0.49) | BCHEL3MBTL1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL18714661 | 0.86 | BCHE (0.45) | BCHEKMT2AMEN1EGFRTSHR | |
| SCHEMBL20696078 | 0.86 | CA12 (0.47) | BCHEL3MBTL1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL5635573 | 0.79 | NOTUM (0.53) | BCHEKMT2AMEN1EGFRTSHR | |
| SCHEMBL13003011 | 0.78 | NR5A1 (0.41) | BCHEKMT2AMEN1EGFRTSHR | |
| SCHEMBL6886131 | 0.78 | KMT2A (0.49) | BCHEKMT2AMEN1TSHRLMNA | |
| SCHEMBL13003010 | 0.78 | KMT2A (0.39) | BCHEKMT2AMEN1EGFRTSHR | |
| SCHEMBL27844785 | 0.75 | SLC22A12 (0.44) | BCHEKMT2AMEN1EGFRTSHR | |
| SCHEMBL3836430 | 0.74 | L3MBTL1 (0.45) | BCHEKMT2AMEN1L3MBTL1NR1H2 | |
| SCHEMBL8083502 | 0.74 | BCHE (0.49) | BCHEKMT2AMEN1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757585-B1 | Anionically substituted 7-Nitroindoline derivatives and their uses | MEDICAL RES COUNCIL (GB) | 2010-12-01 | — | — | EP | disclosed |
| EP-1757585-A1 | Anionically substituted 7-Nitroindoline derivatives and their uses | Medical Research Council (GB) | 2007-02-28 | — | — | EP | disclosed |