SCHEMBL1300350

SCHEMBL1300350

O=Cc1cc([N+](=O)[O-])cc(Br)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.59
MAPT P10636 4/20 0.55
HTT P42858 3/20 0.55
ALDH1A1 P00352 3/20 0.55
LMNA P02545 2/20 0.55
LCK P06239 1/20 0.49
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP3A4 P08684 1/20 0.44
PKM P14618 1/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ALPL P05186 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
RECQL P46063 1/20 0.43
MCL1 Q07820 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30329716 1.00 ERN1 (0.59) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL12492120 0.87 ERN1 (0.69) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL13196182 0.84 MAPT (0.53) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL13625355 0.84 ERN1 (0.58) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL2553752 0.83 LCK (0.51) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL2553753 0.83 LCK (0.51) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL994720 0.82 MEN1 (0.56) MAPTHTTALDH1A1LMNAMEN1
SCHEMBL4756022 0.81 ERN1 (0.63) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL14198033 0.81 MAPT (0.54) ERN1MAPTHTTALDH1A1LMNA
SCHEMBL14977336 0.80 MAPT (0.60) ERN1MAPTHTTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192584-A Siloxane modified terpyridine corrosion-resistant auxiliary agent and application thereof in preparation of intrinsic metal corrosion-resistant epoxy resin coating 厦门大学深圳研究院 2024-12-27 CN claimed
CN-117209741-A Preparation method of Schiff base catalyst and preparation method of polyglycolic acid 中国科学院长春应用化学研究所 2023-12-12 CN claimed
CN-113563740-A Anti-corrosion functional filler and preparation method and application thereof 厦门大学 2021-10-29 CN claimed
CN-109134300-B AIE compound and preparation method and application thereof 晋中学院 2021-05-14 CN claimed
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP claimed
CN-106082199-A A kind of graphene composite film and preparation method thereof 烟台市烯能新材料股份有限公司 2016-11-09 CN claimed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN claimed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN claimed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP claimed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO claimed
CN-119192584-A Siloxane modified terpyridine corrosion-resistant auxiliary agent and application thereof in preparation of intrinsic metal corrosion-resistant epoxy resin coating 厦门大学深圳研究院 2024-12-27 CN disclosed
US-20240368139-A1 NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF TANGO THERAPEUTICS, INC. 2024-11-07 US disclosed
CN-118647610-A Novel modulators of EHMT1 and EHMT2 and therapeutic uses thereof 探戈医药股份有限公司 2024-09-13 CN disclosed
CN-117343304-A Double-center Schiff base catalyst and preparation method thereof, and preparation method of polyglycolic acid 中国科学院长春应用化学研究所 2024-01-05 CN disclosed
CN-117343305-A Tri-center Schiff base catalyst and preparation method thereof and preparation method of polyglycolide 中国科学院长春应用化学研究所 2024-01-05 CN disclosed
WO-2001009122-A2 SEROTONERGIC BENZOFURANS ELI LILLY AND COMPANY (US) 2001-02-08 WO disclosed
WO-2000078768-A1 POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2000-12-28 WO disclosed
WO-2000044737-A1 AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS ELI LILLY AND COMPANY (US) 2000-08-03 WO disclosed
US-4281855-A Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein CIBA-GEIGY CORPORATION (US) 1981-08-04 US disclosed
US-4183553-A CARBONLESS COPYING CIBA-GEIGY CORPORATION (US) 1980-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368139-A1 NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF EHMT1, EHMT2, SHMT1 ERN1 972/4885MAPT 2171/4885HTT 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.