Sugi Predict

Sugi Predict / Compounds / SCHEMBL994720

SCHEMBL994720

SCHEMBL994720

O=[N+]([O-])c1cc(Br)c(O)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ HTT P42858 3/20 0.56
▸ LMNA P02545 2/20 0.56
▸ ALDH1A1 P00352 5/20 0.55
▸ CYP3A4 P08684 2/20 0.55
▸ GPR35 Q9HC97 4/20 0.52
▸ MAPT P10636 2/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ TTR P02766 1/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ HPGD P15428 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ ALOX12 P18054 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ PMP22 Q01453 1/20 0.52
▸ HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17132338 0.89 ALDH1A1 (0.62) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL8329477 0.87 GPR35 (0.66) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL482509 0.86 MEN1 (0.74) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL13735277 0.86 ALDH1A1 (0.65) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL8327908 0.86 GPR35 (0.65) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL11942497 0.86 ALDH1A1 (0.47) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL980505 0.86 ALDH1A1 (0.47) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL4660845 0.86 ALDH1A1 (0.48) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL14744103 0.86 GPR35 (0.65) MEN1KMT2AHTTLMNAALDH1A1
SCHEMBL11643518 0.85 ALDH1A1 (0.50) MEN1KMT2AHTTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613745-A Preparation method and application of series of zirconium-based MOFs and electrochromic film thereof 南开大学 2025-03-14 — — CN claimed
CN-118549570-A Detection method of 13 disinfection byproducts in sediment 上海市环境科学研究院 2024-08-27 — — CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 — — CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 — — CN claimed
CN-113025155-A Preparation method of bio-based coating with high anti-corrosion property 南京工业大学 2021-06-25 — — CN claimed
CN-110482653-A A kind of framework metal catalyst activates newborn hydrogen and is applied to halogenated aryl hydrocarbon rapid hydrogenation dehalogenation method in water environment UNIV DONGGUAN TECHNOLOGY 2019-11-22 — — CN claimed
US-9604929-B2 Functionalized carbon nanoparticles and functional polymer fibers prepared using the same KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2017-03-28 — — US claimed
US-20150204009-A1 FUNCTIONALIZED CARBON NANOPARTICLES AND FUNCTIONAL POLYMER FIBERS PREPARED USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-07-23 — — US claimed
US-20260085048-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO INC (US) 2026-03-26 — — US disclosed
US-12441689-B2 ACSS2 inhibitors and methods of use thereof EPIVARIO, INC. (US) 2025-10-14 — — US disclosed
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO, INC. 2025-06-12 — — US disclosed
CN-119613745-A Preparation method and application of series of zirconium-based MOFs and electrochromic film thereof 南开大学 2025-03-14 — — CN disclosed
US-12133852-B2 ACSS2 inhibitors and methods of use thereof EPIVARIO, INC. (US) 2024-11-05 — — US disclosed
CN-118549570-A Detection method of 13 disinfection byproducts in sediment 上海市环境科学研究院 2024-08-27 — — CN disclosed
US-4170614-A HYDROLYSIS OF TRIS(2,6-DIHALOPHENYL) PHOSPHATE PPG INDUSTRIES, INC. (US) 1979-10-09 — — US disclosed
US-4125628-A FORMALDEHYDE, QUATERNARY AMMONIUM SALT VINELAND LABORATORIES, INC. (US) 1978-11-14 — — US disclosed
US-4106924-A HERBICIDES ICI AUSTRALIA LIMITED (AU) 1978-08-15 — — US disclosed
US-4059655-A REACTING A 2,6-DIHALOPHENOL WITH PHOSPHORUS OXYHALIDE, HYDROLYSIS PPG INDUSTRIES, INC. (US) 1977-11-22 — — US disclosed
US-4022911-A Disinfectant composition comprising a quaternary ammonium compound, a phenol, and formaldehyde DAMON CORPORATION (US) 1977-05-10 — — US disclosed
US-3930837-A 3-CHLORO-5-ACETAMIDAISOQUINOLINE AS A HERBICIDE ICI AUSTRALIA LIMITED (AU) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ADSS2 MEN1 1305/4885KMT2A 1401/4885HTT 4784/4885
US-20260085048-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ACSL3 MEN1 2249/4885KMT2A 1477/4885HTT 4847/4885
US-12133852-B2 ACSS2 inhibitors and methods of use thereof ACSS2, GLS2, ADSS2 MEN1 1305/4885KMT2A 1401/4885HTT 4784/4885
US-12441689-B2 ACSS2 inhibitors and methods of use thereof ACSS2, ADSS2, GLS2 MEN1 658/4885KMT2A 924/4885HTT 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.