Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640203 | 0.94 | ALOX15 (0.43) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9065399 | 0.90 | ALOX15 (0.46) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9806689 | 0.88 | SMN1; SMN2 (0.41) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL254353 | 0.88 | SMN1; SMN2 (0.41) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1152835 | 0.86 | SMN1; SMN2 (0.42) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL16847424 | 0.83 | SMN1; SMN2 (0.36) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL2321698 | 0.82 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9806691 | 0.82 | SMN1; SMN2 (0.41) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10850510 | 0.82 | SMN1; SMN2 (0.41) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL670857 | 0.82 | SMN1; SMN2 (0.41) | ALOX15SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765780-B2 | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20110269791-A1 | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269791-A1 | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use | HSD11B1, CYP46A1, HSD11B2 | ALOX15 159/4885SMN1; SMN2 3476/4885ALDH1A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.