SCHEMBL13005154

SCHEMBL13005154

CN(C)C(Cc1ccccc1)C(=O)c1ccc(N2CCOCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
ALDH1A1 P00352 5/20 0.61
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
SMN1; SMN2 Q16637 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
MAOB P27338 1/20 0.46
GSK3B P49841 1/20 0.46
RORC P51449 3/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
LMNA P02545 1/20 0.44
AOC3 Q16853 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537643 0.90 ALDH1A1 (0.49) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL15453193 0.89 NPC1 (0.51) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL755565 0.86 MAPT (0.48) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL38651071 0.85 RORC (0.46) MAPTALDH1A1SMN1; SMN2L3MBTL1MAOB
SCHEMBL15548441 0.84 SMN1; SMN2 (0.48) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL27923385 0.83 MAPT (0.48) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL966444 0.83 GSK3B (0.51) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL28140901 0.82 MAPT (0.45) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL27877917 0.82 GSK3B (0.50) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL13892504 0.81 SMN1; SMN2 (0.49) MAPTALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1958994-B1 Ink set for inkjet recording and inkjet recording method FUJIFILM CORP (JP) 2010-12-08 EP disclosed