SCHEMBL537643

SCHEMBL537643

CC(Cc1ccccc1)CC(C(=O)c1ccc(N2CCOCC2)cc1)N(C)C

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MAPT P10636 4/20 0.49
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
RORC P51449 5/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 1/20 0.43
MAOB P27338 1/20 0.42
HIF1A Q16665 1/20 0.42
ACACB O00763 1/20 0.42
GSK3B P49841 1/20 0.41
CTSL P07711 1/20 0.41
CTSK P43235 1/20 0.41
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13005154 0.90 MAPT (0.61) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL38651071 0.82 RORC (0.46) ALDH1A1MAPTSMN1; SMN2RORCL3MBTL1
SCHEMBL755565 0.81 MAPT (0.48) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL15453193 0.80 NPC1 (0.51) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL28488511 0.80 CTSL (0.50) ALDH1A1MAPTSMN1; SMN2RORCL3MBTL1
SCHEMBL15548441 0.80 SMN1; SMN2 (0.48) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL27923385 0.79 MAPT (0.48) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL966444 0.79 GSK3B (0.51) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL28140901 0.78 MAPT (0.45) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL27877917 0.78 GSK3B (0.50) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414462-A1 COATING COMPOSITION, (METH)ACRYL-POLYMER AND MONOMER MIXTURE FOR PRODUCING SAID (METH)ACRYL-POLYMER Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
WO-2010112474-A1 COATING COMPOSITION, (METH)ACRYL-POLYMER AND MONOMER MIXTURE FOR PRODUCING SAID (METH)ACRYL-POLYMER EVONIK RÖHM GMBH (DE) 2010-10-07 WO disclosed