Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228667 | 0.96 | PSEN1 (0.38) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL8323320 | 0.86 | PTPN1 (0.51) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL133377 | 0.86 | PTPN1 (0.51) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL13098203 | 0.85 | PTPN1 (0.44) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL13098233 | 0.82 | PSEN1 (0.38) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL383065 | 0.81 | PSEN1 (0.47) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL8319088 | 0.80 | PTPN1 (0.52) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL3190513 | 0.77 | PTPN1 (0.49) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| Trifluoromethanesulfonic Acid SCHEMBL8862138 | 0.76 | PTPN1 (0.48) | PTPN1MAPTLMNAPOLBCYP2C9 | |
| SCHEMBL12228664 | 0.76 | PTPN1 (0.43) | PTPN1MAPTLMNAPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324329-A1 | COMPOUND | JSR CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324329-A1 | COMPOUND | AFF2, AFF1, AFF4 | PTPN1 3434/4885MAPT 3626/4885LMNA 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.