Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.61 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.61 |
| ▸ | CETP | P11597 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005440 | 0.88 | CALM1 (0.59) | CALM1CAMKK2CETPTSHRKDM4E | |
| SCHEMBL13005637 | 0.87 | CALM1 (0.52) | CALM1CAMKK2CETPTSHRHSD17B10 | |
| SCHEMBL13005718 | 0.87 | CALM1 (0.71) | CALM1CAMKK2TSHRKDM4EALDH1A1 | |
| SCHEMBL13060700 | 0.83 | CALM1 (0.65) | CALM1CAMKK2CETPTSHRHSD17B10 | |
| SCHEMBL8174800 | 0.82 | CETP (0.54) | CETPTSHRHSD17B10PTGESKDM4E | |
| SCHEMBL13005607 | 0.82 | BCHE (0.56) | CALM1CAMKK2BCHEMEN1KMT2A | |
| SCHEMBL13005430 | 0.82 | CALM1 (0.52) | CALM1CAMKK2BCHE | |
| SCHEMBL13005625 | 0.81 | BCHE (0.47) | CALM1CAMKK2CETPTSHRBCHE | |
| SCHEMBL13005546 | 0.80 | CALM1 (0.47) | CALM1CAMKK2CETPTSHRKDM4E | |
| SCHEMBL13005414 | 0.80 | BCHE (0.56) | CALM1CAMKK2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |