SCHEMBL13006148

SCHEMBL13006148

CC(=O)OCCc1ccc(CCc2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.43
CHRM2 P08172 3/20 0.39
CHRM4 P08173 3/20 0.39
CHRM5 P08912 3/20 0.39
CHRM1 P11229 3/20 0.39
CHRM3 P20309 3/20 0.39
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
LMNA P02545 2/20 0.37
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14448404 0.93 RAD52 (0.47) RAD52CHRM2CHRM4CHRM5CHRM1
SCHEMBL14448406 0.89 CYP2A6 (0.42) RAD52CHRM2CHRM4CHRM5CHRM1
SCHEMBL8652676 0.88 LMNA (0.45) RAD52CHRM2CHRM4CHRM5CHRM1
SCHEMBL13777821 0.86 RAD52 (0.48) RAD52CHRM5CHRM1CHRM3RAB9A
SCHEMBL14981836 0.85 THRB (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL22448171 0.84 CTDSP1 (0.43) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL13839851 0.84 THRB (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9915741 0.84 THRB (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL13153783 0.82 THRB (0.46) ALDH1A1TSHR
SCHEMBL14063394 0.82 ALDH1A1 (0.55) POLBRAB9AALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100316423-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-12-16 US disclosed