Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775101 | 0.76 | TLR8 (0.38) | ALDH1A1SMN1; SMN2MAPTEGLN3CASP1 | |
| SCHEMBL17389142 | 0.74 | CHEK1 (0.45) | ALDH1A1SLC29A1CYP1A2LMNAPOLB | |
| SCHEMBL17433048 | 0.74 | ALDH1A1 (0.59) | ALDH1A1SLC29A1CYP1A2LMNAPOLB | |
| SCHEMBL30559809 | 0.68 | AXL (0.44) | ALDH1A1SLC29A1CYP1A2LMNAPOLB | |
| SCHEMBL23609029 | 0.66 | KDM4E (0.46) | ALDH1A1SMN1; SMN2POLBHPGDKMT2A | |
| SCHEMBL28701478 | 0.66 | MAPT (0.50) | SLC29A1CYP1A2SMN1; SMN2LMNAPOLB | |
| SCHEMBL29366544 | 0.66 | MAPT (0.50) | SLC29A1CYP1A2SMN1; SMN2LMNAPOLB | |
| SCHEMBL23609238 | 0.64 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL29829135 | 0.64 | POLB (0.68) | ALDH1A1CYP1A2SMN1; SMN2LMNAPOLB | |
| SCHEMBL17017090 | 0.64 | POLB (0.68) | ALDH1A1CYP1A2SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317646-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | ALDH1A1 2975/4885SLC29A1 2127/4885CYP1A2 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.