Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100085 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TRPA1HDAC8TSHRCHRNB2 | |
| SCHEMBL27813923 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TRPA1HDAC8TSHRCHRNB2 | |
| SCHEMBL31494225 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TRPA1HDAC8TSHRCHRNB2 | |
| SCHEMBL19856497 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TRPA1HDAC8TSHRCHRNB2 | |
| SCHEMBL13007289 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TRPA1HDAC8TSHR | |
| SCHEMBL13397832 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL13007290 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TRPA1 | |
| SCHEMBL6436939 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TRPA1HDAC8TSHR | |
| SCHEMBL13007293 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TRPA1 | |
| SCHEMBL8024564 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TRPA1HDAC8TSHRCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851547-B2 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20070212557-A1 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |