SCHEMBL19856497

SCHEMBL19856497

C=Cc1ccc(-c2ccc([Si](OC)(OC)OC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TRPA1 O75762 1/20 0.35
TSHR P16473 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
DAPK3 O43293 1/20 0.32
JAK2 O60674 1/20 0.32
ABL1 P00519 1/20 0.32
NTRK1 P04629 1/20 0.32
FYN P06241 1/20 0.32
CSF1R P07333 1/20 0.32
RET P07949 1/20 0.32
MET P08581 1/20 0.32
PDGFRB P09619 1/20 0.32
FGFR1 P11362 1/20 0.32
FLT3 P36888 1/20 0.32
MAPK8 P45983 1/20 0.32
GSK3B P49841 1/20 0.32
CDK9 P50750 1/20 0.32
RPS6KA3 P51812 1/20 0.32
LIMK1 P53667 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27813923 0.94 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8CHRNB2
SCHEMBL100085 0.94 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8CHRNB2
SCHEMBL3353844 0.82 ESR2 (0.33) ABL1TP53
SCHEMBL31494225 0.81 ALDH1A1 (0.41) ALDH1A1TRPA1TSHRHDAC8CHRNB2
SCHEMBL13007288 0.81 ALDH1A1 (0.41) ALDH1A1TRPA1TSHRHDAC8CHRNB2
SCHEMBL30018341 0.79 ALDH1A1 (0.39) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL6436939 0.79 ALDH1A1 (0.39) ALDH1A1TRPA1TSHRHDAC8
SCHEMBL20872887 0.78 ALDH1A1 (0.43) ALDH1A1TRPA1TSHRDAPK3JAK2
SCHEMBL5888561 0.77 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8DAPK3
SCHEMBL5012806 0.77 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085145-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DAINIPPON INK & CHEMICALS (JP) 2026-03-26 US disclosed
EP-4628517-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DIC Corporation (JP) 2025-10-08 EP disclosed
WO-2025070077-A1 CURABLE RESIN COMPOSITION, CURED ARTICLE, AND OPTICAL WAVEGUIDE DIC株式会社 2025-04-03 WO disclosed
WO-2025047282-A1 OPTICAL WAVEGUIDE AND METHOD FOR MANUFACTURING OPTICAL WAVEGUIDE 日産化学株式会社 2025-03-06 WO disclosed
WO-2024116861-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DIC株式会社 2024-06-06 WO disclosed
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
WO-2022211070-A1 REACTIVE SILSESQUIOXANE COMPOUND-CONTAINING POLYMERIZABLE COMPOSITION FOR OPTICAL WAVEGUIDE 日産化学株式会社 2022-10-06 WO disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
US-10787535-B2 Polymerizable composition containing reactive silsesquioxane compound containing phenanthrene ring NISSAN CHEMICAL CORPORATION (JP) 2020-09-29 US disclosed
US-20200148875-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2020-05-14 US disclosed
US-20190292324-A1 POLYMERIZABLE COMPOSITION COMPRISING REACTIVE SILSESQUIOXANE COMPOUND AND AROMATIC VINYL COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-09-26 US disclosed
US-20190169345-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING NISSAN CHEMICAL CORPORATION (JP) 2019-06-06 US disclosed
EP-3327049-B1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND NISSAN CHEMICAL CORP (JP) 2019-05-29 EP disclosed
US-10253126-B2 Optical waveguide-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-09 US disclosed
US-20180305488-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-25 US disclosed
EP-3373051-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-09-12 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20180079849-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-3281959-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085145-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE MAT1A, CAPZA1, CDH1 ALDH1A1 376/4885TRPA1 696/4885TSHR 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.