SCHEMBL100085

SCHEMBL100085

C=Cc1ccc([Si](OC)(OC)OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.39
TRPA1 O75762 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TDP1 Q9NUW8 2/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
TP53 P04637 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27813923 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL19856497 0.94 ALDH1A1 (0.44) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL31494225 0.86 ALDH1A1 (0.41) ALDH1A1TSHRTRPA1HDAC8CHRNB2
SCHEMBL13007288 0.86 ALDH1A1 (0.41) ALDH1A1TSHRTRPA1HDAC8CHRNB2
SCHEMBL6436939 0.85 ALDH1A1 (0.39) ALDH1A1TSHRTRPA1HDAC8TAS1R3
SCHEMBL5014438 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL5012806 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTRPA1HDAC8TDP1
SCHEMBL3350851 0.81 CYP1A2 (0.43) ALDH1A1TSHRTRPA1TP53
SCHEMBL3350857 0.81 CYP1A2 (0.43) ALDH1A1TSHRTRPA1TP53
SCHEMBL18393996 0.81 TRPA1 (0.40) ALDH1A1TRPA1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5262 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978258-B Mud-resistant slump-retaining polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2026-05-15 CN claimed
US-20250353967-A1 CURABLE SILOXANE RESIN COMPOSITION AND FILM INCLUDING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-20 US claimed
CN-119978258-A Mud-resistant slump-retaining polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2025-05-13 CN claimed
EP-4540297-A1 PHOTOCURABLE COMPOSITIONS AND METHODS FOR DELIVERING RADIATION TO A SUBJECT Theragenics Corporation (US) 2025-04-23 EP claimed
CN-119752318-A Photosensitive polyimide coating adhesive and preparation method and application thereof 波米科技有限公司 2025-04-04 CN claimed
CN-119613630-A Graft copolymer composition, ABS resin, and preparation method and application thereof 辽宁金发科技有限公司 2025-03-14 CN claimed
CN-119462728-A Method for preparing 4-trimethoxy silicon-based styrene and application thereof 南通晶爱微电子科技有限公司 2025-02-18 CN claimed
CN-119431666-A High cis-polybutadiene elastomer and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-119410148-A High-heat-conductivity low-oil-precipitation low-thermal-resistance silicone grease 烟台德邦科技股份有限公司 2025-02-11 CN claimed
CN-119330799-A Solid propellant and preparation method thereof 中国人民解放军国防科技大学 2025-01-21 CN claimed
EP-0759457-B2 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2004-06-16 EP claimed
EP-1226971-B1 Ink jet printing paper SHINETSU CHEMICAL CO (JP) 2004-03-17 EP claimed
US-20030228120-A1 Optical waveguide, optical transmitter and receiver module, and laminated structure SANYO ELECTRIC CO., LTD. (JP) 2003-12-11 US claimed
EP-0659817-B1 Method for the preparation of an acrylic rubber-based composition NISSIN CHEMICAL IND (JP) 2001-10-10 EP claimed
EP-0759457-B1 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2001-06-13 EP claimed
US-5814703-A ORGANIC RESIN AND SILICONE COMPOUND; PROTECTIVE COATINGS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-09-29 US claimed
US-5672661-A MOLDING MATERIAL SUITABLE FOR HOT-AIR VULCANIZATION UNDER NORMAL PRESSURE COMPRISING A POLYMER OF AN ALKOXYALKYL ACRYLATE, AN ALKYL ACRYLATE, AN UNSATURATED ALKOXYSILANE, A REINFORCING FILLER AND AN ORGANIC PEROXIDE; KINETICS NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 1997-09-30 US claimed
EP-0759457-A2 Weather and soiling-resistant silicone-containing coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-02-26 EP claimed
US-5585424-A Acrylic rubber-based composition NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 1996-12-17 US claimed
EP-0659817-A1 Acrylic rubber-based composition NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 1995-06-28 EP claimed