Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.62 |
| ▸ | NOS1 | P29475 | 2/20 | 0.62 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9610889 | 0.79 | IDO1 (0.62) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL5450413 | 0.79 | NOS1 (1.00) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL3321590 | 0.77 | IDO1 (1.00) | IDO1NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL3815185 | 0.76 | IDO1 (1.00) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL9612336 | 0.76 | IDO1 (0.61) | IDO1NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL20677852 | 0.74 | IDO1 (0.62) | IDO1NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL31383506 | 0.74 | IDO1 (0.96) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL8496431 | 0.74 | FFAR1 (0.44) | — | |
| SCHEMBL11940544 | 0.73 | IDO1 (0.54) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL1146034 | 0.72 | GAA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |