Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.61 |
| ▸ | NOS1 | P29475 | 2/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20677852 | 0.98 | IDO1 (0.62) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL14450873 | 0.84 | DAO (0.45) | IDO1NOS1DAO | |
| SCHEMBL12620405 | 0.81 | DAO (0.43) | IDO1DAO | |
| SCHEMBL13356156 | 0.78 | DAO (0.50) | DAO | |
| SCHEMBL3773147 | 0.76 | IDO1 (1.00) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL9610889 | 0.76 | IDO1 (0.62) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL13007612 | 0.76 | IDO1 (0.62) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL5450413 | 0.75 | NOS1 (1.00) | IDO1NOS1NOS3NOS2 | |
| SCHEMBL688551 | 0.75 | DAO (0.50) | DAO | |
| SCHEMBL1146015 | 0.75 | DAO (0.50) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031624-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | UNIV RUTGERS (US) | 2019-01-31 | — | — | US | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9012654-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8912222-B2 | Method to control insects resistant to common insecticides | DOW AGROSCIENCES, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140315840-A1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | CORTEVA AGRISCIENCE LLC | 2014-10-23 | — | — | US | disclosed |
| US-8846717-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES, LLC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140135362-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8669278-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | DOW AGROSCIENCES, LLC. (US) | 2014-03-11 | — | — | US | disclosed |
| US-20130288897-A1 | SYNERGISTIC PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | US | disclosed |
| US-20090325892-A1 | Synergistic pesticidal mixtures | DOW AGROSCIENCES LLC (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090325892-A1 | Synergistic pesticidal mixtures | DOW AGROSCIENCES LLC (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2009134224-A1 | SYNERGISTIC PESTICIDAL MIXTURES | DOW AGROSCIENCES LLC (US) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009014891-A2 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| US-20070299264-A1 | Method to control insects resistant to common insecticides | DOW AGROSCIENCES LLC | 2007-12-27 | — | — | US | disclosed |
| US-20070299264-A1 | Method to control insects resistant to common insecticides | DOW AGROSCIENCES LLC | 2007-12-27 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031624-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | ABCB11, SLC10A1, SLC47A1 | IDO1 3165/4885NOS1 1199/4885NOS3 1492/4885 |
| US-20090023782-A1 | INCREASING PLANT VIGOR | HDLBP, VPS4B, VPS28 | IDO1 2360/4885NOS1 1691/4885NOS3 1416/4885 |
| US-20140315840-A1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DDT, AGPS, SMOX | IDO1 1135/4885NOS1 3321/4885NOS3 2667/4885 |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | NPEPPS, HDHD5, PRDX6 | IDO1 218/4885NOS1 2192/4885NOS3 628/4885 |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | NPEPPS, PRDX6, HDHD5 | IDO1 200/4885NOS1 1719/4885NOS3 453/4885 |
| US-20070299264-A1 | Method to control insects resistant to common insecticides | DDT, GSS, AS3MT | IDO1 1362/4885NOS1 980/4885NOS3 449/4885 |
| US-20090325892-A1 | Synergistic pesticidal mixtures | ACHE, DDT, PDE1C | IDO1 312/4885NOS1 2538/4885NOS3 825/4885 |
| US-20130288897-A1 | SYNERGISTIC PESTICIDAL COMPOSITIONS | DDT, ACHE, DPP3 | IDO1 319/4885NOS1 2886/4885NOS3 1254/4885 |
| US-20140135362-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | NPEPPS, HDHD5, PRDX6 | IDO1 218/4885NOS1 2192/4885NOS3 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.