Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557061 | 0.88 | MAPK1 (0.53) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL14557071 | 0.83 | ESR2 (0.49) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL889831 | 0.83 | MAPK1 (0.61) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL1104367 | 0.81 | CYP2C9 (0.41) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL14431999 | 0.81 | MEN1 (0.48) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL1104437 | 0.80 | L3MBTL1 (0.56) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL14112997 | 0.80 | PTGS2 (0.50) | MAPK1HTTESR2ESR1MEN1 | |
| SCHEMBL10353247 | 0.76 | RPS6KB1 (0.54) | MAPK1HTTTSHRRPS6KB1ROCK1 | |
| SCHEMBL14112995 | 0.76 | NPSR1 (0.49) | MAPK1HTTESR2ESR1TSHR | |
| SCHEMBL14557250 | 0.73 | HTT (0.40) | MAPK1HTTESR2ESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259140-A1 | IMMERSION AUTOMATIC DEVELOPMENT APPARATUS AND AUTOMATIC DEVELOPMENT METHOD FOR MANUFACTURING PLANOGRAPHIC PRINTING PLATE | FUJIFILM Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |