SCHEMBL1104437

SCHEMBL1104437

Cc1ccc(-n2c(S)nc3ccccc32)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ESR2 Q92731 5/20 0.46
ESR1 P03372 4/20 0.46
NTRK1 P04629 1/20 0.44
NTRK2 Q16620 1/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
TSHR P16473 1/20 0.44
GRIA1 P42261 1/20 0.42
CACNG8 Q8WXS5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14557061 0.91 MAPK1 (0.53) L3MBTL1MAPK1HTTMEN1ALDH1A1
SCHEMBL14557071 0.86 ESR2 (0.49) L3MBTL1MAPK1HTTMEN1ALDH1A1
SCHEMBL889831 0.85 MAPK1 (0.61) L3MBTL1MAPK1HTTMEN1ALDH1A1
SCHEMBL14112997 0.83 PTGS2 (0.50) MAPK1HTTMEN1NPC1ALDH1A1
SCHEMBL7760076 0.82 MAPK1 (0.79) L3MBTL1MAPK1HTTMEN1NPC1
SCHEMBL10353247 0.82 RPS6KB1 (0.54) MAPK1HTTMEN1NPC1ALDH1A1
SCHEMBL14112993 0.82 MAPK1 (0.50) L3MBTL1MAPK1HTTMEN1NPC1
SCHEMBL13008656 0.80 MAPK1 (0.44) L3MBTL1MAPK1HTTMEN1NPC1
SCHEMBL13863180 0.80 ALDH1A1 (0.51) MAPK1HTTNPC1ALDH1A1HSD17B10
SCHEMBL15214855 0.79 L3MBTL1 (0.56) L3MBTL1MAPK1HTTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
EP-2503393-B2 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2016-07-20 EP disclosed
EP-2088468-B1 Method of preparing lithographic printing plate and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
EP-2662729-A1 Method for preparation of lithographic printing plate Fujifilm Corporation (JP) 2013-11-13 EP disclosed
EP-2503393-B1 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2013-11-13 EP disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
EP-1829681-A2 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM Corporation (JP) 2007-09-05 EP disclosed
EP-1640805-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-08-22 EP disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed