Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886493 | 1.00 | AKR1C3 (0.38) | AKR1C3AKR1C1GAAALDH1A1SLC18A3 | |
| SCHEMBL12639524 | 1.00 | AKR1C3 (0.38) | AKR1C3AKR1C1GAAALDH1A1SLC18A3 | |
| SCHEMBL1878836 | 1.00 | AKR1C3 (0.38) | AKR1C3AKR1C1GAAALDH1A1SLC18A3 | |
| SCHEMBL12639641 | 0.77 | SLC18A3 (0.35) | AKR1C3AKR1C1GAASLC18A3SIGMAR1 | |
| SCHEMBL30918597 | 0.77 | SLC18A3 (0.35) | AKR1C3AKR1C1GAASLC18A3SIGMAR1 | |
| SCHEMBL13010462 | 0.77 | SRD5A1 (0.39) | AKR1C3AKR1C1GAASLC18A3SIGMAR1 | |
| SCHEMBL13010456 | 0.77 | KDM1A (0.39) | AKR1C3AKR1C1GAAALDH1A1SLC18A3 | |
| SCHEMBL12672475 | 0.77 | ALDH1A1 (0.37) | AKR1C3AKR1C1GAAALDH1A1SLC18A3 | |
| SCHEMBL24488134 | 0.72 | MAP1LC3B (0.35) | ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL20228466 | 0.72 | HTR2C (0.35) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317866-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100317866-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| WO-2009101162-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | BASF SE (DE) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317866-A1 | IMIDAZOLE GROUP-CONTAINING PHOSPHORUS COMPOUNDS | ITPA, PPIP5K2, IPMK | AKR1C3 3698/4885AKR1C1 4046/4885GAA 2368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.