SCHEMBL13010487

SCHEMBL13010487

COCCOc1ccccc1N1CCOCCOCCOCCOCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.49
KDM1A O60341 1/20 0.48
POLB P06746 2/20 0.48
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
DRD2 P14416 4/20 0.46
DRD3 P35462 4/20 0.46
DRD4 P21917 1/20 0.46
HRH2 P25021 1/20 0.46
HRH1 P35367 1/20 0.46
P2RY12 Q9H244 1/20 0.46
ALDH1A1 P00352 4/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
KDM4E B2RXH2 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
AKT1 P31749 1/20 0.44
HTT P42858 1/20 0.43
ADRA1A P35348 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12528231 1.00 AKR1C3 (0.49) AKR1C3KDM1APOLBMAPTSMN1; SMN2
SCHEMBL20630891 0.85 POLB (0.48) AKR1C3POLBMAPTSMN1; SMN2DRD2
SCHEMBL70658 0.85 DRD2 (0.44) AKR1C3KDM1APOLBMAPTSMN1; SMN2
SCHEMBL20630878 0.83 P2RY12 (0.49) KDM1APOLBMAPTSMN1; SMN2P2RY12
SCHEMBL8342129 0.82 POLB (0.54) AKR1C3POLBMAPTSMN1; SMN2DRD2
SCHEMBL12527305 0.82 GAA (0.52) KDM1AMAPTSMN1; SMN2P2RY12ALDH1A1
SCHEMBL12527300 0.81 AKR1C3 (0.68) AKR1C3POLBMAPTDRD2DRD3
SCHEMBL25548398 0.80 CCR5 (0.43) AKR1C3KDM1AMAPTDRD2DRD3
SCHEMBL13723948 0.80 GAA (0.54) KDM1AMAPTSMN1; SMN2P2RY12ALDH1A1
SCHEMBL3173622 0.79 AKR1C3 (0.70) AKR1C3POLBMAPTDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858383-B2 Chromoionophore and method of determining sodium ions OPTI MEDICAL SYSTEMS (US) 2010-12-28 US disclosed
US-20070259444-A1 ions are contacted with a compound having chromophoric and ionophoric moieties; the ionophoric moiety interacts with the ions present resulting in the chromophoric moiety changing its radiation absorption properties in the ultraviolet and visible regions of the spectrum; whole blood, plasma, serum, urine OPTI MEDICAL SYSTEMS, INC. 2007-11-08 US disclosed