Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477795 | 0.88 | KCNH2 (0.41) | HTR1APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL90902 | 0.87 | KCNH2 (0.42) | HTR1APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL12629236 | 0.86 | HTR1A (0.43) | DRD2HTR1AHTR2AHTR7ADRA1A | |
| SCHEMBL10088452 | 0.86 | ALDH1A3 (0.45) | MEN1KMT2AALDH1A1KCNH2P2RY12 | |
| SCHEMBL20630878 | 0.85 | P2RY12 (0.49) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL12528231 | 0.85 | AKR1C3 (0.49) | DRD2ADRA1APOLBALDH1A1P2RY12 | |
| SCHEMBL13010487 | 0.85 | AKR1C3 (0.49) | DRD2ADRA1APOLBALDH1A1P2RY12 | |
| SCHEMBL16477808 | 0.85 | KCNH2 (0.43) | HTR1APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL25548398 | 0.83 | CCR5 (0.43) | DRD2HTR1ASCN9AMEN1KMT2A | |
| SCHEMBL70655 | 0.79 | AKR1C3 (0.49) | POLBMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129365-B2 | Water-soluble, fluorescent compounds for detection of potassium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129365-B2 | Water-soluble, fluorescent compounds for detection of potassium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-18 | — | — | US | disclosed |
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | TACR2, KCNJ8, TAC3 | DRD2 2411/4885HTR1A 2250/4885HTR2A 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.