Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411441 | 0.97 | L3MBTL1 (0.71) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL27536208 | 0.88 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL10066488 | 0.86 | L3MBTL1 (0.72) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL1300632 | 0.84 | L3MBTL1 (0.70) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL15265754 | 0.84 | L3MBTL1 (0.70) | L3MBTL1DAOMETRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6565113 | 0.83 | L3MBTL1 (0.68) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL13130238 | 0.83 | L3MBTL1 (1.00) | L3MBTL1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1075209 | 0.82 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL12720575 | 0.82 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL13197072 | 0.82 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149099-A2 | IMIDAZO[4,5-C]-PYRIDINE-4-ON-DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-10-31 | — | — | EP | claimed |
| WO-2000040583-A2 | IMIDAZO[4,5-C]-PYRIDINE-4-ON-DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-07-13 | — | — | WO | claimed |
| CN-119390668-A | Compound with ketoxime ether structure and application thereof | 复旦大学 | 2025-02-07 | — | — | CN | disclosed |
| US-10085986-B2 | Pyrimidinone compounds and their use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-10-02 | — | — | US | disclosed |
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9376426-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9376426-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9284300-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-03-15 | — | — | US | disclosed |
| US-9284300-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-03-15 | — | — | US | disclosed |
| US-9221806-B2 | 2-(heterocyclylbenzyl)pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| CN-1315942-A | 2-oxo-j(2H)-quinoline derivatives | MERCK PATENT GMBH (DE) | 2001-10-03 | — | — | CN | disclosed |
| EP-1117664-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GmbH (DE) | 2001-07-25 | — | — | EP | disclosed |
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000051989-A1 | PYRAZOLE-3-ON-DERIVATIVE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2000-09-08 | — | — | WO | disclosed |
| WO-2000020416-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GMBH (DE) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10085986-B2 | Pyrimidinone compounds and their use | TPMT, DHFR, DPYD | L3MBTL1 3615/4885DAO 934/4885MET 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.