Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301049 | 0.97 | L3MBTL1 (0.70) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL27536208 | 0.85 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL13130238 | 0.84 | L3MBTL1 (1.00) | L3MBTL1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL10066488 | 0.83 | L3MBTL1 (0.72) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL1300632 | 0.82 | L3MBTL1 (0.70) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL15265754 | 0.82 | L3MBTL1 (0.70) | L3MBTL1DAOMETRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6565113 | 0.81 | L3MBTL1 (0.68) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL31346685 | 0.79 | RAB9A (0.53) | L3MBTL1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1075209 | 0.79 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 | |
| SCHEMBL12720575 | 0.79 | L3MBTL1 (0.66) | L3MBTL1DAOMETRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492384-B1 | Imidazo (4,5-C) pyridine-4-one derivatives with factor XA inhibiting effect | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1117664-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GmbH (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020416-A1 | IMIDAZO[4,5-C-]-PYRIDINE-4-ONE DERIVATIVES WITH FACTOR XA INHIBITING EFFECT | MERCK PATENT GMBH (DE) | 2000-04-13 | — | — | WO | disclosed |