Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203871 | 1.00 | KMT2A (0.41) | KMT2AWDR5PDE10ACYP1A2CYP3A4 | |
| SCHEMBL13061874 | 0.91 | L3MBTL1 (0.42) | KMT2AWDR5PDE10AAGXTHPGD | |
| SCHEMBL13061873 | 0.91 | L3MBTL1 (0.42) | KMT2AWDR5PDE10AAGXTHPGD | |
| SCHEMBL5197626 | 0.86 | KMT2A (0.41) | KMT2AWDR5PDE10ACYP1A2CYP3A4 | |
| SCHEMBL4958916 | 0.86 | KMT2A (0.41) | KMT2AWDR5PDE10ACYP1A2CYP3A4 | |
| SCHEMBL9446038 | 0.86 | WDR5 (0.38) | KMT2AWDR5PDE10ACYP1A2CYP3A4 | |
| SCHEMBL9709017 | 0.85 | KMT2A (0.39) | KMT2AWDR5PDE10AAGXTHPGD | |
| SCHEMBL9708898 | 0.85 | WDR5 (0.42) | KMT2AWDR5PDE10AAGXTHSP90AA1 | |
| SCHEMBL10720384 | 0.84 | KMT2A (0.38) | KMT2AWDR5PDE10AAGXTHPGD | |
| Water SCHEMBL4555319 | 0.84 | KMT2A (0.40) | KMT2AWDR5PDE10ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324298-A1 | Novel Process for the Preparation of Esomeprazole and Salts Thereof | APOTEX PHARMACHEM INC. (CA) | 2010-12-23 | — | — | US | disclosed |
| US-7786309-B2 | Process for the preparation of esomeprazole and salts thereof | APOTEX PHARMACHEM INC. (CA) | 2010-08-31 | — | — | US | disclosed |
| US-20070287839-A1 | Novel process for the preparation of esomeprazole and salts thereof | APOTEX PHARMACHEM INC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287839-A1 | Novel process for the preparation of esomeprazole and salts thereof | ARSA, RPS28, RPL41 | KMT2A 4318/4885WDR5 4246/4885PDE10A 2346/4885 |
| US-20100324298-A1 | Novel Process for the Preparation of Esomeprazole and Salts Thereof | ARSA, RPS28, RPL41 | KMT2A 4318/4885WDR5 4246/4885PDE10A 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.