Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.33 |
| ▸ | ATP4B | P51164 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720384 | 0.99 | KMT2A (0.38) | KMT2AWDR5ALDH1A1KDM4EPDE10A | |
| SCHEMBL9279388 | 0.87 | KMT2A (0.40) | KMT2AWDR5ALDH1A1PDE10AHPGD | |
| SCHEMBL13136704 | 0.86 | PKM (0.42) | KMT2AWDR5ALDH1A1KDM4EPDE10A | |
| SCHEMBL13011306 | 0.85 | KMT2A (0.41) | KMT2AWDR5ALDH1A1KDM4EPDE10A | |
| SCHEMBL13203871 | 0.85 | KMT2A (0.41) | KMT2AWDR5ALDH1A1KDM4EPDE10A | |
| SCHEMBL9446025 | 0.85 | KMT2A (0.40) | KMT2AWDR5ALDH1A1KDM4EPDE10A | |
| SCHEMBL13061874 | 0.82 | L3MBTL1 (0.42) | KMT2AWDR5ALDH1A1PDE10AHPGD | |
| SCHEMBL13061873 | 0.82 | L3MBTL1 (0.42) | KMT2AWDR5ALDH1A1PDE10AHPGD | |
| SCHEMBL9445964 | 0.82 | L3MBTL1 (0.43) | KMT2AWDR5ALDH1A1KDM4EPDE10A | |
| SCHEMBL9708898 | 0.81 | WDR5 (0.42) | KMT2AWDR5PDE10AHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233284-B1 | PHARMACOLOGICAL COMPOUNDS | Aktiebolaget Hässle (SE) | 1992-08-19 | — | — | EP | disclosed |