Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474018 | 1.00 | LMNA (0.47) | LMNAHTTKDM4EMEN1KMT2A | |
| SCHEMBL13014489 | 0.84 | KMT2A (0.50) | LMNAHTTKDM4EMEN1KMT2A | |
| SCHEMBL353219 | 0.81 | PRKCI (0.35) | KDM4EMEN1KMT2ATP53NPC1 | |
| SCHEMBL115015 | 0.80 | P2RX1 (0.44) | MEN1KMT2ANPC1RAB9AP2RX1 | |
| SCHEMBL5471851 | 0.75 | LMNA (0.45) | LMNAHTTKDM4EMEN1KMT2A | |
| Dehydroxymethylepoxyquinomicin SCHEMBL1669417 | 0.72 | PARK7 (0.54) | LMNAHTTKDM4EMEN1KMT2A | |
| Dehydroxymethylepoxyquinomicin SCHEMBL14491796 | 0.72 | PARK7 (0.54) | LMNAHTTKDM4EMEN1KMT2A | |
| Dehydroxymethylepoxyquinomicin SCHEMBL14504317 | 0.72 | PARK7 (0.54) | LMNAHTTKDM4EMEN1KMT2A | |
| Dehydroxymethylepoxyquinomicin SCHEMBL1671089 | 0.72 | PARK7 (0.54) | LMNAHTTKDM4EMEN1KMT2A | |
| SCHEMBL5706486 | 0.68 | MEN1 (0.44) | LMNAHTTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148042-A1 | OXABICYCLO [4.1.O]HEPT-B-EN-S-YLCARBAMOYL DERIVATIVES INHIBITING THE NUCLEAR FACTOR-KAPPA(B) - (NF-KB) | PROFECTUS BIOSCIENCES, INC. (US) | 2010-12-23 | — | — | WO | disclosed |