Dehydroxymethylepoxyquinomicin

Dehydroxymethylepoxyquinomicin

SCHEMBL1671089

O=C(NC1=CC(=O)[C@H]2O[C@H]2[C@H]1O)c1ccccc1O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARK7 Q99497 1/20 0.54
LMNA P02545 6/20 0.45
HTT P42858 5/20 0.45
KDM4E B2RXH2 5/20 0.45
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
TP53 P04637 4/20 0.45
HSD17B10 Q99714 4/20 0.45
NPC1 O15118 4/20 0.45
HPGD P15428 3/20 0.45
GAA P10253 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.41
MPO P05164 1/20 0.41
HIF1A Q16665 1/20 0.41
RAB9A P51151 3/20 0.41
POLB P06746 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydroxymethylepoxyquinomicin SCHEMBL14491796 1.00 PARK7 (0.54) PARK7LMNAHTTKDM4EMEN1
Dehydroxymethylepoxyquinomicin SCHEMBL1669417 1.00 PARK7 (0.54) PARK7LMNAHTTKDM4EMEN1
Dehydroxymethylepoxyquinomicin SCHEMBL14504317 1.00 PARK7 (0.54) PARK7LMNAHTTKDM4EMEN1
SCHEMBL666087 0.85 PARK7 (0.64) PARK7LMNAHTTKDM4EMEN1
SCHEMBL666050 0.84 PARK7 (0.50) PARK7LMNAHTTKDM4EMEN1
SCHEMBL666185 0.84 P2RX1 (0.51) PARK7MEN1KMT2AKCNMA1P2RX1
SCHEMBL666528 0.84 PARK7 (0.50) PARK7LMNAHTTKDM4EMEN1
SCHEMBL665039 0.84 PARK7 (0.50) PARK7LMNAHTTKDM4ENPC1
SCHEMBL352816 0.84 PARK7 (0.48) PARK7LMNAHTTKDM4EMEN1
SCHEMBL167099 0.84 PARK7 (0.50) PARK7HTTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024199144-A1 NOVEL REAGENT FOR MITIGATING LNP TOXICITY SHANGHAI MOYIN THERAPEUTICS CO., LTD. (CN) 2024-10-03 WO claimed
CN-116474104-A Small molecule targeting pharmaceutical composition for treating medulloblastoma 南京医科大学 2023-07-25 CN claimed
CN-115429807-A Dehydroepoxymethoquinone mycin and its use for treating psoriasis 深圳万和制药有限公司 2022-12-06 CN claimed
US-11450409-B2 Determination of NFkB pathway activity using unique combination of target genes INNOSIGN B.V. (NL) 2022-09-20 US claimed
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS MODEL MEDICINES INC (US) 2026-05-07 US disclosed
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES MODEL MEDICINES INC (US) 2026-04-16 US disclosed
EP-3893882-B1 CXCR7 INHIBITORS FOR THE TREATMENT OF CANCER CHEMOCENTRYX INC (US) 2026-04-15 EP disclosed
EP-4705765-A2 BUCCAL CELL DIAGNOSIS OF RISK IN FAMILIAL ARRHYTHMIA SYNDROMES Beth Israel Deaconess Medical Center, Inc. (US) 2026-03-11 EP disclosed
US-12559525-B2 Conjugated fibronectin-binding peptides for use in tumor or fibrosis diagnosis and therapy ETH Zürich (CH) 2026-02-24 US disclosed
US-12551475-B2 Methods and compositions for treating RNA viral infections MODEL MEDICINES, INC. (US) 2026-02-17 US disclosed
US-12534536-B2 Natural killer cells expressing a chimeric antigen receptor that binds CD38 ONK THERAPEUTICS LIMITED (IE) 2026-01-27 US disclosed
EP-4667008-A2 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2025-12-24 EP disclosed
US-20120088827-A1 Oxabicyclo[4.1.0]Hept-B-en-S-yl Carbamoyl Derivatives Inhibiting The Nuclear Factor-Kappa (B) - (NF-KB) PROFECTUS BIOSCIENCES, INC. (US) 2012-04-12 US disclosed
US-20120046357-A1 Benzamide and Napthamide Derivatives Inhibiting Nuclear Factor-Kappa (B) - (NK-kB) PROFECTUS BIOSCIENCES, INC. (US) 2012-02-23 US disclosed
US-20120015952-A1 Inhibitors of NF-KB PROFECTUS BIOSCIENCES, INC. (US) 2012-01-19 US disclosed
WO-2010148042-A1 OXABICYCLO [4.1.O]HEPT-B-EN-S-YLCARBAMOYL DERIVATIVES INHIBITING THE NUCLEAR FACTOR-KAPPA(B) - (NF-KB) PROFECTUS BIOSCIENCES, INC. (US) 2010-12-23 WO disclosed
WO-2010127058-A1 BENZAMIDE AND NAPHTHAMIDE DERIVATIVES INHIBITING NUCLEAR FACTOR- KAP PA (B) - (NF-KB) PROFECTUS BIOSCIENCES, INC. (US) 2010-11-04 WO disclosed
WO-2010111460-A1 INHIBITORS OF NF-KB PROFECTUS BIOSCIENCES, INC. (US) 2010-09-30 WO disclosed
US-20070142465-A1 Macrophage activation inhibitor SIGNAL CREATION INC. (JP) 2007-06-21 US disclosed
US-20070142465-A1 Macrophage activation inhibitor SIGNAL CREATION INC. (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559525-B2 Conjugated fibronectin-binding peptides for use in tumor or fibrosis diagnosis and therapy FN1, ASNS, FNIP1 PARK7 3210/4885LMNA 454/4885HTT 3452/4885
US-12551475-B2 Methods and compositions for treating RNA viral infections SARS1, EIF2AK2, SNRPE PARK7 2039/4885LMNA 1401/4885HTT 1907/4885
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES ESR1, VDR, POLL PARK7 2336/4885LMNA 92/4885HTT 3429/4885
US-20120015952-A1 Inhibitors of NF-KB NFKBIA, IKBKB, IKBKG PARK7 3327/4885LMNA 3191/4885HTT 4538/4885
US-20070142465-A1 Macrophage activation inhibitor CD209, MSR1, ARG1 PARK7 3295/4885LMNA 3392/4885HTT 4670/4885
US-12534536-B2 Natural killer cells expressing a chimeric antigen receptor that binds CD38 TNFRSF9, TNFRSF1A, CD40 PARK7 2892/4885LMNA 1933/4885HTT 1117/4885
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS SARS1, NSUN2, NSUN3 PARK7 2879/4885LMNA 2152/4885HTT 2657/4885
US-20120046357-A1 Benzamide and Napthamide Derivatives Inhibiting Nuclear Factor-Kappa (B) - (NK-kB) NFKBIA, IKBKB, NFKB1 PARK7 3384/4885LMNA 1408/4885HTT 4212/4885
US-20120088827-A1 Oxabicyclo[4.1.0]Hept-B-en-S-yl Carbamoyl Derivatives Inhibiting The Nuclear Factor-Kappa (B) - (NF-KB) NFKBIA, NFRKB, IKBKB PARK7 3595/4885LMNA 3540/4885HTT 4495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.