Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21512458 | 0.98 | DNM1 (0.49) | DNM1DGKANAAAHTR2CALDH1A1 | |
| SCHEMBL12792545 | 0.93 | NAAA (0.53) | DNM1DGKANAAAHTR2CMGLL | |
| SCHEMBL10820524 | 0.93 | NAAA (0.53) | DNM1DGKANAAAHTR2CMGLL | |
| SCHEMBL25801067 | 0.93 | NAAA (0.53) | DNM1DGKANAAAHTR2CMGLL | |
| SCHEMBL15015609 | 0.93 | DGKA (0.53) | DNM1DGKANAAAHTR2CALDH1A1 | |
| SCHEMBL2006674 | 0.93 | DGKA (0.53) | DNM1DGKANAAAHTR2CALDH1A1 | |
| SCHEMBL27959766 | 0.92 | NAAA (0.55) | DNM1DGKANAAAHTR2CMGLL | |
| SCHEMBL12120249 | 0.91 | DGKA (0.55) | DNM1DGKANAAAHTR2CALDH1A1 | |
| SCHEMBL25963499 | 0.91 | NAAA (0.50) | DNM1DGKANAAAHTR2CMGLL | |
| SCHEMBL889188 | 0.89 | DNM1 (0.42) | DNM1DGKANAAAHTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266954-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | Draximage, Inc. (CA) | 2010-12-29 | — | — | EP | disclosed |
| EP-2266953-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | Draximage, Inc. (CA) | 2010-12-29 | — | — | EP | disclosed |