Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282385 | 0.87 | HTR2C (0.51) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL8301426 | 0.87 | ALDH1A1 (0.43) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL17234175 | 0.78 | HTR2C (0.58) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL29979939 | 0.78 | HTR2C (0.58) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL29587713 | 0.77 | HTR2C (0.59) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL9546447 | 0.76 | HTR2C (0.57) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL11151887 | 0.74 | HTR2C (0.49) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL6625918 | 0.74 | FKBP1A (0.52) | HTR2CALDH1A1CYP3A4TSHRNPC1 | |
| SCHEMBL29587180 | 0.74 | HCRTR2 (0.57) | HTR2CCPB1AGTR2CYP2C9CYP2C19 | |
| SCHEMBL12282046 | 0.74 | HTR2C (0.51) | HTR2CCPB1AGTR2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264030-A1 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | Incyte Corporation (US) | 2010-12-22 | — | — | EP | disclosed |