Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21030127 | 0.81 | GBA1 (0.33) | CYP3A4DPP4 | |
| SCHEMBL2790991 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL501823 | 0.62 | ALDH1A1 (0.39) | — | |
| SCHEMBL13634299 | 0.61 | MEN1 (0.41) | — | |
| SCHEMBL17304541 | 0.61 | HTT (0.38) | — | |
| SCHEMBL16461836 | 0.61 | MAPT (0.31) | — | |
| SCHEMBL5844067 | 0.60 | PDK2 (0.37) | — | |
| SCHEMBL13061648 | 0.60 | GRIN1 (0.34) | CYP3A4 | |
| SCHEMBL7723639 | 0.60 | ALOX15 (0.37) | — | |
| SCHEMBL426303 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261223-A1 | Pyrimidine derivatives used as pi-3 kinase inhibitors | Novartis AG (CH) | 2010-12-15 | — | — | EP | disclosed |