Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777542 | 0.80 | NPSR1 (0.37) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL7033536 | 0.80 | ALDH1A1 (0.59) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL8926859 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL6652226 | 0.75 | ALDH1A1 (0.60) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL6628817 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CA12CA1CA7CA9 | |
| 114, 10,10-Dimethyl-11-Demethyl-12-Oxo Calanolide A SCHEMBL13016680 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL8467499 | 0.75 | ALDH1A1 (0.63) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL13016937 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL13016588 | 0.75 | CA12 (0.62) | ALDH1A1CA12CA1CA7CA9 | |
| SCHEMBL14220543 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216335-B1 | TETRACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF | INST MATERIA MEDICA CAMS (CN) | 2014-03-12 | — | — | EP | disclosed |
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
| EP-2216335-A1 | TETRIACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF | Institute of Mataria Medica, Chinese Academy of Medical Sciences (CN) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | TBCB, TBC1D15, TBC1D5 | ALDH1A1 482/4885CA12 4246/4885CA1 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.