SCHEMBL13017261

SCHEMBL13017261

C(=C/c1ccc(-c2ccccn2)cc1)\c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.50
LMNA P02545 3/20 0.50
CYP1A2 P05177 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
RAB9A P51151 1/20 0.47
KDM1A O60341 3/20 0.46
TLR4 O00206 1/20 0.46
TLR2 O60603 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18572781 0.90 KDM1A (0.49) KDM4ELMNACYP1A2CCR1CCR5
(Z)-1,2-Diphenylethene SCHEMBL28562270 0.87 KDM4E (0.67) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL21565118 0.85 CYP1A2 (0.47) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL7027876 0.85 KDM4E (0.46) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL4818701 0.85 KDM4E (0.46) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL29567108 0.85 CYP1A2 (0.47) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL11827477 0.83 HDAC2 (0.56) KDM4ELMNAP4HTMNPC1MAPT
SCHEMBL11827474 0.83 HDAC2 (0.56) KDM4ELMNAP4HTMNPC1MAPT
SCHEMBL1566968 0.82 KDM4E (0.72) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL30989133 0.82 KDM4E (0.72) KDM4ELMNACYP1A2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019215427-A1 PROCESS FOR FORMING A CARBON-CARBON BOND THE UNIVERSITY OF MANCHESTER (GB) 2019-11-14 WO disclosed
EP-1501907-B1 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE ENTPR LTD (GB) 2016-07-27 EP disclosed
US-9023978-B2 Solution-processable phosphorescent materials CAMBRIDGE ENTERPRISE LTD. (GB) 2015-05-05 US disclosed
US-9023978-B2 Solution-processable phosphorescent materials CAMBRIDGE ENTERPRISE LTD. (GB) 2015-05-05 US disclosed
EP-2264123-A2 Solution-processable phosphorescent materials Cambridge Display Technology Limited (GB) 2010-12-22 EP disclosed
US-20100264812-A1 METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-21 US disclosed
US-20100264812-A1 METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-21 US disclosed
EP-1932851-A1 METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100264812-A1 METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE SOD1, CRY1, YAP1 KDM4E 4016/4885LMNA 3982/4885CYP1A2 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.