SCHEMBL249836

SCHEMBL249836

C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC(OC(=O)CCC(=O)OC5CC(=O)C=C6CC[C@@H]7[C@H]([C@@H](O)C[C@@]8(C)[C@H]7CC[C@]8(O)C(=O)CO)[C@]65C)[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO.[NaH].[NaH]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 13/20 0.64
▸ HSD17B10 Q99714 5/20 0.64
▸ NR3C1 P04150 4/20 0.64
▸ PGR P06401 4/20 0.64
▸ SERPINA6 P08185 4/20 0.64
▸ CYP3A4 P08684 4/20 0.64
▸ SMN1; SMN2 Q16637 4/20 0.64
▸ CYP2C19 P33261 3/20 0.64
▸ NR3C2 P08235 3/20 0.64
▸ KMT2A Q03164 3/20 0.64
▸ NFKB1 P19838 2/20 0.64
▸ MAPT P10636 2/20 0.64
▸ SHBG P04278 2/20 0.64
▸ AR P10275 2/20 0.59
▸ ABCB11 O95342 1/20 0.59
▸ TNF P01375 1/20 0.59
▸ IL6 P05231 1/20 0.59
▸ GLUL P15104 1/20 0.59
▸ ADAM17 P78536 1/20 0.59
▸ GPBAR1 Q8TDU6 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14931695 1.00 HIF1A (0.64) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL6001323 0.99 HIF1A (0.65) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL27571456 0.97 HIF1A (0.61) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL27941428 0.97 HIF1A (0.61) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL1301994 0.96 HIF1A (0.62) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL1535104 0.96 HIF1A (0.63) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL141828 0.95 HIF1A (0.62) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL28809123 0.95 HIF1A (0.66) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL41085 0.94 HIF1A (0.63) HIF1AHSD17B10NR3C1PGRSERPINA6
SCHEMBL141360 0.94 HIF1A (0.61) HIF1AHSD17B10NR3C1PGRSERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2526968-A2 Nogo receptor antagonists Biogen Idec MA Inc. (US) 2012-11-28 — — EP claimed
WO-2007089601-A9 NOGO RECEPTOR ANTAGONISTS BIOGEN IDEC INC (US) 2008-12-18 — — WO claimed
EP-1981902-A2 NOGO RECEPTOR ANTAGONISTS Biogen Idec MA Inc. (US) 2008-10-22 — — EP claimed
WO-2007089601-A2 NOGO RECEPTOR ANTAGONISTS BIOGEN IDEC MA INC. (US) 2007-08-09 — — WO claimed
EP-1740187-A1 MACULAR EDEMA PATIENT SELECTION METHOD AND TREATMENT WITH EYE IMPLANT COMPRISING A STEROID Bausch & Lomb Incorporated (US) 2007-01-10 — — EP claimed
WO-2005099717-A1 MACULAR EDEMA PATIENT SELECTION METHOD AND TREATMENT WITH EYE IMPLANT COMPRISING A STEROID BAUSCH & LOMB INCORPORATED (US) 2005-10-27 — — WO claimed
US-20050226814-A1 Diagnostic method and kit for implantation of a sustained release drug-delivery implant with a steroid BAUSCH & LOMB INCORPORATED 2005-10-13 — — US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 — — CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed
EP-0786999-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1999-01-20 — — EP claimed
EP-0792371-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1998-12-30 — — EP claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 — — EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 — — EP claimed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 — — CN claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 — — US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 — — WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 — — WO claimed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 — — EP claimed
US-20250304667-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN INC (US) 2025-10-02 — — US disclosed
CN-114716544-B Complement component C5 antibodies 阿勒根公司 2024-10-01 — — CN disclosed
US-20240294652-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN K-A, INC. 2024-09-05 — — US disclosed
US-20240279317-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN INC (US) 2024-08-22 — — US disclosed
US-11858999-B2 IL-17 receptor A antigen binding proteins AMGEN K-A, INC. (US) 2024-01-02 — — US disclosed
US-20230124150-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN, INC. 2023-04-20 — — US disclosed
CN-114480253-B Culture medium for directional induced differentiation of pluripotent stem cells into hepatocytes, culture method and application 深圳市三启生物技术有限公司 2023-02-28 — — CN disclosed
CN-115515634-A Methods of treating Crohn's disease with anti-IL 23 specific antibodies 詹森生物科技公司 2022-12-23 — — CN disclosed
CN-115427444-A Safe and effective methods for treating ulcerative colitis with anti-IL 12/IL23 antibodies 詹森生物科技公司 2022-12-02 — — CN disclosed
CN-114716544-A Complement component C5 antibody 阿勒根公司 2022-07-08 — — CN disclosed
EP-4008726-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN, INC. (US) 2022-06-08 — — EP disclosed
CN-114480253-A Culture medium for directional induced differentiation of pluripotent stem cells into hepatocytes, culture method and application 深圳市三启生物技术有限公司 2022-05-13 — — CN disclosed
US-20220047773-A1 SELF-ELIMINATING COATINGS INTERFACE BIOLOGICS, INC. (CA) 2022-02-17 — — US disclosed
US-20220040385-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS INTERFACE BIOLOGICS, INC. (CA) 2022-02-10 — — US disclosed
CN-107207585-B Complement component C5 antibody 阿勒根公司 2021-12-21 — — CN disclosed
EP-3165539-B1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN K A INC (US) 2021-12-08 — — EP disclosed
US-11180564-B2 IL-17 Receptor A antigen binding proteins AMGEN K-A, INC. (US) 2021-11-23 — — US disclosed
US-20210101965-A1 COMPLEMENT COMPONENT C5 ANTIBODIES XENCOR, INC. 2021-04-08 — — US disclosed
CN-106456751-B Method for treating nail and scalp psoriasis 安姆根K-A有限公司 2021-02-02 — — CN disclosed
US-20200362045-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN K-A, INC. 2020-11-19 — — US disclosed
US-20200317762-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN INC (US) 2020-10-08 — — US disclosed
US-10752678-B2 Complement component C5 antibodies ALLERGAN, INC. (US) 2020-08-25 — — US disclosed
US-20200197310-A1 Technology for Preparation of Macromolecular Microspheres NEXBIO, INC. 2020-06-25 — — US disclosed
EP-3107935-B1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN INC (US) 2020-06-24 — — EP disclosed
EP-3653643-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN, INC. (US) 2020-05-20 — — EP disclosed
US-10604563-B2 Nucleic acids encoding anti-complement Factor Bb antibodies ALLERGAN, INC. (US) 2020-03-31 — — US disclosed
US-10583086-B2 Technology for preparation of macromolecular microspheres ANSUN BIOPHARMA, INC. (US) 2020-03-10 — — US disclosed
CN-110724691-A Complement factor Bb antibodies 阿勒根公司 2020-01-24 — — CN disclosed
CN-106232624-B Complement factor Bb antibodies 阿勒根公司 2020-01-21 — — CN disclosed
US-20190298889-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS INTERFACE BIOLOGICS, INC. (CA) 2019-10-03 — — US disclosed
EP-3126392-B1 METHODS OF TREATING NAIL AND SCALP PSORIASIS KIRIN AMGEN INC (US) 2019-09-11 — — EP disclosed
US-20190262426-A1 Hydrogel-Linked IL-1ra Prodrug ASCENDIS PHARMA A/S (DK) 2019-08-29 — — US disclosed
EP-1996710-B1 RIFAXIMIN ANTI-RECTAL DYSFUNCTION PREPARATION SALIX PHARMACEUTICALS INC (US) 2019-08-14 — — EP disclosed
EP-3054982-B1 HYDROGEL-LINKED IL-1RA PRODRUG ASCENDIS PHARMA AS (DK) 2019-05-01 — — EP disclosed
US-10231938-B2 Transdermal drug delivery device including an occlusive backing NOVEN PHARMACEUTICALS, INC. (US) 2019-03-19 — — US disclosed
US-20190071492-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN INC (US) 2019-03-07 — — US disclosed
US-10208122-B2 IL-17 receptor A antigen binding proteins AMGEN K-A, INC. (US) 2019-02-19 — — US disclosed
US-10195311-B2 Local delivery of drugs from self assembled coatings INTERFACE BIOLOGICS, INC. (CA) 2019-02-05 — — US disclosed
US-10093724-B2 Methods of treating a complement associated eye condition by administering complement factor Bb antibodies ALLERGAN, INC. (US) 2018-10-09 — — US disclosed
US-20180222969-A1 COMPLEMENT COMPONENT C5 ANTIBODIES XENCOR, INC. 2018-08-09 — — US disclosed
US-10039864-B2 Oligofluorinated cross-linked polymers and uses thereof INTERFACE BIOLOGICS, INC. (CA) 2018-08-07 — — US disclosed
US-9932395-B2 Nucleic acids encoding complement component C5 antibodies ALLERGAN, INC. (US) 2018-04-03 — — US disclosed
US-20180071219-A1 Technology for Preparation of Macromolecular Microspheres NEXBIO, INC. 2018-03-15 — — US disclosed
US-20180057576-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN, INC. 2018-03-01 — — US disclosed
US-20180042996-A1 Hydrogel-Linked IL-1ra Prodrug ASCENDIS PHARMA OSTEOARTHRITIS DIVISION A/S (DK) 2018-02-15 — — US disclosed
US-20180028449-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2018-02-01 — — US disclosed
US-20180028721-A1 SELF-ELIMINATING COATINGS INTERFACE BIOLOGICS, INC. (CA) 2018-02-01 — — US disclosed
EP-2203498-B1 OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF INTERFACE BIOLOGICS INC (CA) 2017-12-06 — — EP disclosed
US-20170340781-A1 OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF Evonik Canada Inc. (CA) 2017-11-30 — — US disclosed
US-20170306007-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN, INC. 2017-10-26 — — US disclosed
US-9796776-B2 Complement factor Bb antibodies ALLERGAN, INC. (US) 2017-10-24 — — US disclosed
US-9701743-B2 Complement component C5 antibodies ALLERGAN, INC. (US) 2017-07-11 — — US disclosed
US-20170174772-A1 METHODS OF TREATING NAIL AND SCALP PSORIASIS KIRIN-AMGEN, INC. (US) 2017-06-22 — — US disclosed
US-9682043-B2 Method of preparation of mixed phase co-crystals with active agents MEDCRYSTALFORMS, LLC (US) 2017-06-20 — — US disclosed
EP-3165539-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS Kirin-Amgen, Inc. (US) 2017-05-10 — — EP disclosed
US-20170114140-A1 IL-17RA-IL-17RB ANTAGONISTS AND USES THEREOF KIRIN-AMGEN INC (US) 2017-04-27 — — US disclosed
US-20170079920-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2017-03-23 — — US disclosed
EP-2487188-B1 IL-17 receptor A antigen binding proteins KIRIN-AMGEN INC (US) 2017-03-08 — — EP disclosed
CN-106456751-A Methods of treating nail and scalp psoriasis 麒麟-安姆根有限公司 2017-02-22 — — CN disclosed
EP-3126392-A1 METHODS OF TREATING NAIL AND SCALP PSORIASIS Kirin-Amgen, Inc. (US) 2017-02-08 — — EP disclosed
EP-2002846-B1 Combination therapy using an IL-1 inhibitor for treating IL-1 mediated diseases AMGEN INC (US) 2017-01-25 — — EP disclosed
EP-3110845-A1 COMPLEMENT FACTOR BB ANTIBODIES ALLERGAN, INC. (US) 2017-01-04 — — EP disclosed
EP-3107935-A2 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN, INC. (US) 2016-12-28 — — EP disclosed
CN-106232624-A Complement factor Bb antibodies 阿勒根公司 2016-12-14 — — CN disclosed
EP-2214748-B1 SELF-ELIMINATING COATINGS INTERFACE BIOLOGICS INC (CA) 2016-12-07 — — EP disclosed
EP-2518085-B1 IL-17 receptor A antigen binding proteins KIRIN-AMGEN INC (US) 2016-12-07 — — EP disclosed
US-20160251443-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC. 2016-09-01 — — US disclosed
US-20160235675-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2016-08-18 — — US disclosed
EP-3054982-A1 HYDROGEL-LINKED IL-1RA PRODRUG Ascendis Pharma Osteoarthritis Division A/S (DK) 2016-08-17 — — EP disclosed
US-20160208004-A1 IL-17RA-IL-17RB Antagonists and Uses Thereof AMGEN INC (US) 2016-07-21 — — US disclosed
EP-1807033-B1 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMA (US) 2016-07-20 — — EP disclosed
US-20160159878-A1 NOGO Receptor Antagonists BIOGEN MA INC (US) 2016-06-09 — — US disclosed
US-20160159914-A1 IL-17 RECEPTOR A IS REQUIRED FOR IL-17C BIOLOGY AMGEN INC (US) 2016-06-09 — — US disclosed
US-20160128949-A1 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. (US) 2016-05-12 — — US disclosed
US-20160008391-A1 GALACTOSAMINOGALACTAN COMPRISING alpha-1-4 LINKED GALACTOSE AND alpha-1-4 LINKED N-ACETYLGALACTOSAMINE FOR USE IN THE TREATMENT OF AT LEAST ONE INFLAMMATORY DISEASE PASTEUR INSTITUT (FR) 2016-01-14 — — US disclosed
EP-2964196-A1 PHARMACEUTICAL COMPOSITIONS FOR RECTAL ADMINISTRATION Cipla Limited (IN) 2016-01-13 — — EP disclosed
US-20160002278-A1 Pharmaceutical Compositions for Rectal Administration CIPLA LIMITED (MH) 2016-01-07 — — US disclosed
US-9228015-B2 Nogo receptor antagonists and methods of increasing neurite outgrowth BIOGEN IDEC MA INC. (US) 2016-01-05 — — US disclosed
US-20150359746-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2015-12-17 — — US disclosed
CN-105142612-A Pharmaceutical compositions for rectal administration CIPLA LTD 2015-12-09 — — CN disclosed
EP-2945638-A1 GALACTOSAMINOGALACTAN COMPRISING 1-4 LINKED GALACTOSE AND 1-4 LINKED N-ACETYLGALACTOSAMINE FOR USE IN THE TREATMENT OF AT LEAST ONE INFLAMMATORY DISEASE Institut Pasteur (FR) 2015-11-25 — — EP disclosed
US-20150290134-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES NEXBIO, INC. 2015-10-15 — — US disclosed
US-9155712-B2 Transdermal drug delivery device including an occlusive backing NOVEN PHARMACEUTICALS, INC. (US) 2015-10-13 — — US disclosed
WO-2015153144-A1 METHODS OF TREATING NAIL AND SCALP PSORIASIS KIRIN-AMGEN, INC. (US) 2015-10-08 — — WO disclosed
US-20150283304-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS INTERFACE BIOLOGICS, INC. (CA) 2015-10-08 — — US disclosed
WO-2015130826-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN, INC. (US) 2015-09-03 — — WO disclosed
US-20150239966-A1 COMPLEMENT COMPONENT C5 ANTIBODIES XENCOR, INC. (US) 2015-08-27 — — US disclosed
US-20150239987-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN, INC. 2015-08-27 — — US disclosed
WO-2015127134-A2 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN, INC. (US) 2015-08-27 — — WO disclosed
US-9096673-B2 IL-17 receptor A antigen binding proteins KIRIN-AMGEN, INC. (US) 2015-08-04 — — US disclosed
EP-1981902-B1 NOGO RECEPTOR ANTAGONISTS BIOGEN MA INC (US) 2015-07-29 — — EP disclosed
CN-102497864-B Sigma ligands for the prevention or treatment of pain induced by chemotherapy ESTEVE LABOR DR 2015-07-22 — — CN disclosed
US-20150196488-A1 Topical Foam Composition CIPLA LIMITED (IN) 2015-07-16 — — US disclosed
CN-102985089-B Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy ESTEVE LABOR DR 2015-07-15 — — CN disclosed
CN-104758253-A Technology for preparation of macromolecular microspheres NEXBIO INC 2015-07-08 — — CN disclosed
US-20150157578-A1 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. (US) 2015-06-11 — — US disclosed
CN-103214576-B IL-17 receptor A antigen binding proteins AMGEN INC 2015-06-03 — — CN disclosed
WO-2015052154-A1 HYDROGEL-LINKED IL-1RA PRODRUG ASCENDIS PHARMA OSTEOARTHRITIS DIVISION A/S (DK) 2015-04-16 — — WO disclosed
US-8987292-B2 Rifaximin anti-rectal dysfunction preparation SALIX PHARMACEUTICALS, LTD. (US) 2015-03-24 — — US disclosed
US-8962697-B2 Bioreponsive polymers INTERFACE BIOLOGICS INC. (CA) 2015-02-24 — — US disclosed
US-20150050713-A1 Technology for the Preparation of Microparticles NEXBIO, INC. 2015-02-19 — — US disclosed
EP-2076541-B1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS KIRIN AMGEN INC (US) 2015-02-18 — — EP disclosed
US-20140356355-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC (US) 2014-12-04 — — US disclosed
US-8900603-B2 Local delivery of drugs from self assembled coatings INTERFACE BIOLOGICS, INC. (CA) 2014-12-02 — — US disclosed
CN-104151428-A IL-17RA-IL-17RB antagonists and uses thereof AMGEN INC 2014-11-19 — — CN disclosed
US-20140322238-A1 IL-17RA-IL-17RB Antagonists and Uses Thereof AMGEN INC. (US) 2014-10-30 — — US disclosed
WO-2014135891-A1 PHARMACEUTICAL COMPOSITIONS FOR RECTAL ADMINISTRATION CIPLA LIMITED (IN) 2014-09-12 — — WO disclosed
US-8815281-B2 Transdermal drug delivery device including an occlusive backing NOVEN PHARMACEUTICALS, INC. (US) 2014-08-26 — — US disclosed
US-20140234330-A1 IL-17 RECEPTOR A IS REQUIRED FOR IL-17C BIOLOGY AMGEN INC. (US) 2014-08-21 — — US disclosed
US-20140227266-A1 NOGO Receptor Antagonists BIOGEN IDEC MA INC. (US) 2014-08-14 — — US disclosed
EP-2759299-A1 Galactosaminogalactan comprising alpha 1-4 linked galactose and alpha 1-4 linked N-acetylgalactosamine for use in the treatment of at least one inflammatory disease INSTITUT PASTEUR (FR) 2014-07-30 — — EP disclosed
US-8790648-B2 Methods of treating psoriasis using IL-17 receptor A antibodies AMGEN INC. (US) 2014-07-29 — — US disclosed
US-8784893-B2 Polymer formulations for delivery of bioactive agents CARBYLAN THERAPEUTICS, INC. (US) 2014-07-22 — — US disclosed
WO-2014108570-A1 GALACTOSAMINOGALACTAN COMPRISING α1-4 LINKED GALACTOSE AND α1-4 LINKED N-ACETYLGALACTOSAMINE FOR USE IN THE TREATMENT OF AT LEAST ONE INFLAMMATORY DISEASE INSTITUT PASTEUR (FR) 2014-07-17 — — WO disclosed
CN-102037017-B IL-17RA-IL-17RB antagonists and uses thereof AMGEN INC 2014-07-09 — — CN disclosed
US-20140134150-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES ANSUN BIOPHARMA, INC. (US) 2014-05-15 — — US disclosed
CN-103784408-A Technology for the preparation of microparticles ANSUN BIOPHARMA INC 2014-05-14 — — CN disclosed
US-20140099696-A1 Technology for the Preparation of Microparticles ANSUN BIOPHARMA, INC. (US) 2014-04-10 — — US disclosed
US-8669345-B2 Nogo receptor antagonists BIOGEN IDEC MA INC. (US) 2014-03-11 — — US disclosed
US-20140037635-A1 METHODS OF TREATMENT USING IL-17E ANTAGONISTS AMGEN INC. (US) 2014-02-06 — — US disclosed
CN-101541833-B Il-17 receptor a antigen binding proteins KIRIN AMGEN INC 2014-01-29 — — CN disclosed
US-8623419-B2 Technology for preparation of macromolecular microspheres ANSUN BIOPHARMA, INC. (US) 2014-01-07 — — US disclosed
US-20130315988-A1 Pharmaceutical Composition CIPLA LIMITED (IN) 2013-11-28 — — US disclosed
US-20130315998-A1 Topical Foam Composition CIPLA LIMITED (IN) 2013-11-28 — — US disclosed
EP-1294765-B1 Use of an antibody specific for an IL-17 like polypeptide AMGEN INC (US) 2013-11-27 — — EP disclosed
US-8591941-B2 Transdermal drug delivery device including an occlusive backing NOVEN PHARMACEUTICALS, INC. (US) 2013-11-26 — — US disclosed
US-20130302886-A1 Pre-Ligand assembly domain of the IL-17 receptor RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2013-11-14 — — US disclosed
US-8574604-B2 Methods and compositions for the delivery of biologically active agents INTERFACE BIOLOGICS, INC. (CA) 2013-11-05 — — US disclosed
US-8545842-B2 Polynucleotides encoding IL-17 receptor A antigen binding proteins KIRIN-AMGEN, INC. (US) 2013-10-01 — — US disclosed
US-20130202654-A1 Topical Foam Composition CIPLA LIMITED (IN) 2013-08-08 — — US disclosed
EP-2616044-A1 PHARMACEUTICAL COMPOSITION Cilpa Limited (IN) 2013-07-24 — — EP disclosed
EP-2401275-B1 NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY RESPIRATORIUS AB (SE) 2013-07-24 — — EP disclosed
CN-103214576-A IL-17 receptor A antigen binding proteins AMGEN INC 2013-07-24 — — CN disclosed
CN-103221032-A Pharmaceutical composition CIPLA LTD 2013-07-24 — — CN disclosed
US-8460647-B2 Pre-ligand assembly domain of the IL-17 receptor AMGEN INC. (US) 2013-06-11 — — US disclosed
US-20130142834-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS Interface Biiologics, Inc. (CA) 2013-06-06 — — US disclosed
US-20130142799-A1 Angiopoietin-2 Specific Binding Agents AMGEN, INC. (US) 2013-06-06 — — US disclosed
US-8445016-B2 Grafted polymers and uses thereof INTERFACE BIOLOGICS, INC. (CA) 2013-05-21 — — US disclosed
US-8440176-B2 Covalently grafted pharmaceutically active polymers INTERFACE BIOLOGICS, INC. (CA) 2013-05-14 — — US disclosed
US-8435518-B2 Methods of using IL-17 receptor a antibodies KIRIN-AMGEN, INC. (US) 2013-05-07 — — US disclosed
US-8415333-B2 Bronchodilating diazaheteroaryls RESPIRATORIOUS AB (SE) 2013-04-09 — — US disclosed
US-8414914-B2 Compositions for mucosal delivery of agents VIRUN, INC. (US) 2013-04-09 — — US disclosed
CN-102985089-A Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy ESTEVE LABOR DR 2013-03-20 — — CN disclosed
CN-101203250-B Methods and compositions for the delivery of biologically active agents via non-covalent interaction, and formed articles INTERFACE BIOLOGICS INC 2013-03-20 — — CN disclosed
CN-102933658-A Local delivery of drugs from self assembled coatings INTERFACE BIOLOGICS INC 2013-02-13 — — CN disclosed
WO-2013016220-A1 IL-17 RECEPTOR A IS REQUIRED FOR IL-17C BIOLOGY AMGEN INC. (US) 2013-01-31 — — WO disclosed
US-20130004969-A1 IL-17 Heteromeric Receptor Complex AMGEN INC. (US) 2013-01-03 — — US disclosed
US-20120308566-A1 USE OF IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS KIRIN-AMGEN, INC. 2012-12-06 — — US disclosed
US-20120308644-A1 Compositions for mucosal delivery of agents ARCHIMEDES LABORATORIES, INC. 2012-12-06 — — US disclosed
EP-2526968-A2 Nogo receptor antagonists Biogen Idec MA Inc. (US) 2012-11-28 — — EP disclosed
EP-2518085-A1 IL-17 receptor A antigen binding proteins Kirin-Amgen, Inc. (US) 2012-10-31 — — EP disclosed
US-20120269881-A9 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. 2012-10-25 — — US disclosed
EP-2513225-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS Interface Biologics Inc. (CA) 2012-10-24 — — EP disclosed
CN-102724960-A Topical foam composition CIPLA LTD 2012-10-10 — — CN disclosed
CN-102724961-A Topical foam composition CIPLA LTD 2012-10-10 — — CN disclosed
US-20120251547-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN, INC. (US) 2012-10-04 — — US disclosed
EP-2503989-A2 TOPICAL FOAM COMPOSITION Cipla Limited (IN) 2012-10-03 — — EP disclosed
EP-2503988-A2 TOPICAL FOAM COMPOSITION Cipla Limited (IN) 2012-10-03 — — EP disclosed
US-8252323-B2 Compositions for mucosal delivery of agents VIRUN, INC. (US) 2012-08-28 — — US disclosed
EP-2488552-A1 USE OF IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS Amgen Inc. (US) 2012-08-22 — — EP disclosed
EP-2487188-A2 IL-17 receptor A antigen binding proteins Kirin-Amgen Inc. (US) 2012-08-15 — — EP disclosed
EP-1768647-B1 COMPOSITIONS COMPRISING A MUCOADHESIVE PROTEIN AND AN ACTIVE PRINCIPLE FOR MUCOSAL DELIVERY OF SAID AGENT VIRUN INC (US) 2012-08-08 — — EP disclosed
US-20120165762-A1 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. 2012-06-28 — — US disclosed
US-20120157666-A1 INTERFERON-LIKE PROTEINS AND USES THEREOF WELCHER ANDREW (US) 2012-06-21 — — US disclosed
WO-2012076832-A1 SUPPOSITORIES COMPRISING RIFAXIMIN CIPLA LIMITED (IN) 2012-06-14 — — WO disclosed
CN-102497864-A Sigma ligands for the prevention or treatment of pain induced by chemotherapy ESTEVE LABOR DR 2012-06-13 — — CN disclosed
US-20120141590-A1 Technology for the Preparation of Microparticles MALAKHOV MICHAEL (US) 2012-06-07 — — US disclosed
US-20120116062-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES ANSUN BIOPHARMA, INC. 2012-05-10 — — US disclosed
US-8148109-B2 polypeptides and fusion proteins; for diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides AMGEN INC. (US) 2012-04-03 — — US disclosed
WO-2012035283-A1 PHARMACEUTICAL COMPOSITION CIPLA LIMITED (IN) 2012-03-22 — — WO disclosed
EP-1477187-B9 Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents ALLERGAN INC (US) 2012-02-22 — — EP disclosed
US-8119128-B2 Antibodies that bind urokinase-type plasminogen activator and epitopes therefor THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2012-02-21 — — US disclosed
US-20120040942-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS RESPIRATORIUS AB (SE) 2012-02-16 — — US disclosed
US-20120009190-A1 IDENTIFICATION AND METHOD FOR USING THE PRE-LIGAND ASSEMBLY DOMAIN OF THE IL-17 RECEPTOR AMGEN INC. (NY) 2012-01-12 — — US disclosed
CN-101005828-B Compositions comprising a mucoadhesive protein and an active principle for mucosal delivery of said agents VIRUN INC 2012-01-11 — — CN disclosed
EP-2401275-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS Respiratorius AB (SE) 2012-01-04 — — EP disclosed
US-20110311546-A1 Angiopoietin-2 specific binding agents AMGEN, INC. 2011-12-22 — — US disclosed
US-20110274681-A1 HUMAN E3ALPHA UBIQUITIN LIGASE FAMILY AMGEN INC. (US) 2011-11-10 — — US disclosed
EP-1615952-B1 METHODS OF TREATMENT OF INFLAMMATORY DISEASES USING SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC (US) 2011-11-02 — — EP disclosed
EP-2361262-A1 TETRANECTIN TRIMERI ZING MODULE TRUNCATION VARIANTS Anaphore, Inc. (US) 2011-08-31 — — EP disclosed
US-7994291-B2 Human E3α ubiquitin ligase family AMGEN INC. (US) 2011-08-09 — — US disclosed
EP-1477187-B1 Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents ALLERGAN INC (US) 2011-07-13 — — EP disclosed
US-20110166331-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN, INC. (US) 2011-07-07 — — US disclosed
US-20110160438-A1 IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF AMGEN INC. (US) 2011-06-30 — — US disclosed
WO-2011072398-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS INTERFACE BIOLOGICS, INC. (CA) 2011-06-23 — — WO disclosed
WO-2011061519-A2 TOPICAL FOAM COMPOSITION CIPLA LIMITED (IN) 2011-05-26 — — WO disclosed
WO-2011061516-A2 TOPICAL FOAM COMPOSITION CIPLA LIMITED (IN) 2011-05-26 — — WO disclosed
US-20110117184-A1 Compositions for mucosal delivery of agents VIRUN, INC. 2011-05-19 — — US disclosed
US-7943738-B2 IL-17 receptor like molecules and uses thereof AMGEN INC. (US) 2011-05-17 — — US disclosed
US-7939070-B2 IL-17 receptor A antigen binding proteins AMGEN INC. (US) 2011-05-10 — — US disclosed
US-20110104228-A1 SELF-ELIMINATING COATINGS INTERFACE BIOLOGICS, INC (CA) 2011-05-05 — — US disclosed
US-20110097384-A1 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. 2011-04-28 — — US disclosed
CN-102037017-A IL-17RA-IL-17RB antagonists and uses thereof AMGEN INC 2011-04-27 — — CN disclosed
WO-2011046958-A1 USE OF IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC. (US) 2011-04-21 — — WO disclosed
US-20110091508-A1 OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF Interface Biologics ,Inc. (CA) 2011-04-21 — — US disclosed
US-20110081339-A1 METHODS OF USING IL-17 RECEPTOR A ANTIBODIES AMGEN INC. (US) 2011-04-07 — — US disclosed
US-7906140-B2 Compositions for mucosal delivery of agents VIRUN, INC. (US) 2011-03-15 — — US disclosed
US-20110052600-A1 IL-17RA-IL-17RB ANTAGONISTS AND USES THEREOF AMGEN INC. (US) 2011-03-03 — — US disclosed
US-20110033540-A1 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS CARBYLAN THERAPEUTICS, INC. 2011-02-10 — — US disclosed
US-20110008841-A1 POLYNUCLEOTIDES ENCODING IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC. (US) 2011-01-13 — — US disclosed
US-20110008356-A1 IL-17 HETEROMERIC RECEPTOR COMPLEX AMGEN, INC. (US) 2011-01-13 — — US disclosed
US-20100303820-A1 METHODS OF TREATMENT USING IL-17E ANTAGONISTS AMGEN INC. (US) 2010-12-02 — — US disclosed
CN-101903025-A Utilize benzopyrone-type PARP inhibitor for treating method for cancer and compositions BIPAR SCIENCES INC 2010-12-01 — — CN disclosed
US-20100297668-A1 HUMAN E3ALPHA UBIQUITIN LIGASE FAMILY AMGEN INC. (US) 2010-11-25 — — US disclosed
EP-2250200-A2 IL-17RA-IL-17RB ANTAGONISTS AND USES THEREOF AMGEN INC. (US) 2010-11-17 — — EP disclosed
CN-101889022-A Trimeric IL-1Ra ANAPHORE INC 2010-11-17 — — CN disclosed
US-7833527-B2 Using cytokine receptor specific immunoglobulin as therapeutic tool in treatment and prevention of inflammatory, nervous system, skin and autoimmune disorders AMGEN INC. (US) 2010-11-16 — — US disclosed
US-7811791-B2 Interferon-like molecules and uses thereof AMGEN INC. (US) 2010-10-12 — — US disclosed
CN-101848704-A Techniques for preparing microparticles NEXBIO INC 2010-09-29 — — CN disclosed
US-7790674-B2 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2010-09-07 — — US disclosed
WO-2010097410-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS RESPIRATORIUS AB (SE) 2010-09-02 — — WO disclosed
US-7786284-B2 Expression vector comprising nucleotide sequences coding cytokine receptor specific immunoglobulin for treatment and prevention of inflammation, cartilage degradation and bone resorption AMGEN INC. (US) 2010-08-31 — — US disclosed
EP-2214748-A1 SELF-ELIMINATING COATINGS Interface Biologics Inc. (CA) 2010-08-11 — — EP disclosed
EP-2203498-A1 OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF Interface Biologics Inc. (CA) 2010-07-07 — — EP disclosed
US-20100166874-A1 Technology for Preparation of Macromolecular Microspheres NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-07-01 — — US disclosed
US-7745586-B2 Human E3α ubiquitin ligase family AMGEN INC. (US) 2010-06-29 — — US disclosed
EP-2195337-A1 TRIMERIC IL-1RA Anaphore, Inc. (US) 2010-06-16 — — EP disclosed
US-7732587-B2 Nucleic acids encoding truncated soluble tumor necrosis factor AMGEN INC. (US) 2010-06-08 — — US disclosed
WO-2010042243-A1 TETRANECTIN TRIMERI ZING MODULE TRUNCATION VARIANTS ANAPHORE, INC. (US) 2010-04-15 — — WO disclosed
EP-2173327-A2 TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES Nexbio, Inc. (US) 2010-04-14 — — EP disclosed
EP-2170958-A1 IL-17 HETEROMERIC RECEPTOR COMPLEX Amgen Inc. (US) 2010-04-07 — — EP disclosed
US-20100056488-A1 CORTICOSTEROID CONJUGATES AND USES THEREOF THE MCLEAN HOSPITAL CORPORATION (US) 2010-03-04 — — US disclosed
US-20100055068-A1 GRAFTED POLYMERS AND USES THEREOF INTERFACE BIOLOGICS INCORPORATED (CA) 2010-03-04 — — US disclosed
US-20100048520-A1 RIFAXIMIN ANTI-RECTAL DYSFUNCTION PREPARATION SALIX PHARMACEUTICALS, LTD. (US) 2010-02-25 — — US disclosed
US-7666839-B2 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2010-02-23 — — US disclosed
US-7666831-B2 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2010-02-23 — — US disclosed
US-7666832-B2 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2010-02-23 — — US disclosed
US-20100041771-A1 Bioreponsive Polymers INTERFACE BIOLOGICS, INC. 2010-02-18 — — US disclosed
US-20100034862-A1 COVALENTLY GRAFTED PHARMACEUTICALLY ACTIVE POLYMERS INTERFACE BIOLOGICS, INC. (CA) 2010-02-11 — — US disclosed
US-7658924-B2 Angiopoietin-2 specific binding agents AMGEN INC. (US) 2010-02-09 — — US disclosed
US-20100028995-A1 Tetranectin Trimerizing Polypeptides ANAPHORE, INC. 2010-02-04 — — US disclosed
US-20100028345-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC. (US) 2010-02-04 — — US disclosed
EP-2144928-A2 JACQUELINIDENTIFICATION AND METHOD FOR USING THE PRE-LIGAND ASSEMBLY DOMAIN OF THE IL-17 RECEPTOR Amgen Inc. (US) 2010-01-20 — — EP disclosed
US-20090325880-A1 TNF RECEPTOR-LIKE MOLECULES AND USES THEREOF AMGEN INC. 2009-12-31 — — US disclosed
EP-2117513-A2 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS Carbylan Biosurgery, Inc. (US) 2009-11-18 — — EP disclosed
EP-0904112-B1 COMPOSITION COMPRISING IL-1RA AS INTERLEUKIN-1 INHIBITOR AND HYALURONAN AS CONTROLLED RELEASE POLYMER AMGEN INC (US) 2009-11-18 — — EP disclosed
US-20090281287-A1 IL-17 receptor like molecules and uses thereof AMGEN INC. (US) 2009-11-12 — — US disclosed
WO-2009136976-A2 IL-17RA-IL-17RB ANTAGONISTS AND USES THEREOF AMGEN INC (US) 2009-11-12 — — WO disclosed
US-7611857-B2 Identifying a modulator of IL-17 receptor-like polypeptide activity; drug screening; treating inflammation AMGEN INC. (US) 2009-11-03 — — US disclosed
WO-2009129630-A1 COVALENTLY GRAFTED PHARMACEUTICALLY ACTIVE POLYMERS INTERFACE BIOLOGICS INC. (CA) 2009-10-29 — — WO disclosed
CN-101541833-A IL-17 receptor A antigen binding proteins AMGEN INC (US) 2009-09-23 — — CN disclosed
US-20090232799-A1 Antibodies that bind urokinase-type plasminogen activator and epitopes therefor THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2009-09-17 — — US disclosed
US-20090203609-A1 Use of IL-1 inhibitors for treating IL-1 mediated diseases AMGEN INC. 2009-08-13 — — US disclosed
US-7569387-B2 Specifically binds an MK61 polypeptide produced by immunizing an animal AMGEN INC. (US) 2009-08-04 — — US disclosed
US-20090191212-A1 Angiopoietin-2 Specific Binding Agents AMGEN, INC. 2009-07-30 — — US disclosed
EP-2076541-A2 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS Amgen Inc. (US) 2009-07-08 — — EP disclosed
US-20090143276-A1 Trimeric IL-1Ra ANAPHORE, INC. 2009-06-04 — — US disclosed
EP-1317536-B1 TNF RECEPTOR-LIKE MOLECULES AND USES THEREOF AMGEN INC (US) 2009-05-13 — — EP disclosed
US-20090117059-A1 COMPOSITIONS AND METHODS OF USE THEREOF, FOR THE TREATMENT OF ORAL PAIN, COMPRISING CLOVES OR EXTRACTS THEREOF IN COMBINATION WITH A STEROID XVASIVE, INC. 2009-05-07 — — US disclosed
WO-2009049426-A1 SELF-ELIMINATING COATINGS INTERFACE BIOLOGICS INC. (CA) 2009-04-23 — — WO disclosed
US-20090099078-A1 Nogo Receptor Antagonists BIOGEN IDEC MA INC. 2009-04-16 — — US disclosed
US-20090098207-A1 Technology for the Preparation of Microparticles NEXBIO, INC. (US) 2009-04-16 — — US disclosed
US-20090098575-A1 The Human E3alpha Ubiquitin Ligase Family AMGEN INC. (US) 2009-04-16 — — US disclosed
WO-2009048961-A1 TRIMERIC IL-1RA ANAPHORE, INC. (US) 2009-04-16 — — WO disclosed
WO-2009043174-A1 OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF INTERFACE BIOLOGICS INC. (CA) 2009-04-09 — — WO disclosed
CN-101404980-A Preparation Technology of Macromolecular Microspheres NEXBIO INC (US) 2009-04-08 — — CN disclosed
EP-2040758-A2 BIORESPONSIVE POLYMERS Interface Biologics Inc. (CA) 2009-04-01 — — EP disclosed
US-20090074758-A1 IL-17 receptor a antigen binding proteins AMGEN, INC, (US) 2009-03-19 — — US disclosed
US-7491500-B2 Mammalian cytokine; related reagents SCHERING CORPORATION (US) 2009-02-17 — — US disclosed
WO-2009020561-A2 COMPOSITIONS AND METHODS OF USE THEREOF, FOR THE TREATMENT OF ORAL PAIN, COMPRISING CLOVES OR EXTRACT THEREOF IN COMBINATION WITH A STEROID XVASIVE INC. (US) 2009-02-12 — — WO disclosed
WO-2009015286-A2 TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES NEXBIO, INC. (US) 2009-01-29 — — WO disclosed
EP-2010584-A2 GRAFTED POLYMERS AND USES THEREOF Interface Biologics Inc. (CA) 2009-01-07 — — EP disclosed
WO-2008156709-A1 IL-17 HETEROMERIC RECEPTOR COMPLEX AMGEN INC. (US) 2008-12-24 — — WO disclosed
WO-2007089601-A9 NOGO RECEPTOR ANTAGONISTS BIOGEN IDEC INC (US) 2008-12-18 — — WO disclosed
EP-2002846-A2 Combination therapy using an IL-1 inhibitor for treating IL-1 mediated diseases Amgen Inc. (US) 2008-12-17 — — EP disclosed
EP-1996710-A2 RIFAXIMIN ANTI-RECTAL DYSFUNCTION PREPARATION Salix Pharmaceuticals, Inc. (US) 2008-12-03 — — EP disclosed
US-7449555-B2 Antibodies of angiogenesis inhibiting domains CD148 AMGEN INC. (US) 2008-11-11 — — US disclosed
WO-2008131315-A2 JACQUELINIDENTIFICATION AND METHOD FOR USING THE PRE-LIGAND ASSEMBLY DOMAIN OF THE IL-17 RECEPTOR AMGEN INC. (US) 2008-10-30 — — WO disclosed
EP-0831912-B2 IMPROVED FORMULATION FOR CONTROLLED RELEASE OF DRUGS BY COMBINING HYDROPHILIC AND HYDROPHOBIC AGENTS ALLERGAN INC (US) 2008-10-29 — — EP disclosed
EP-1981483-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES Nexbio, Inc. (US) 2008-10-22 — — EP disclosed
EP-1981902-A2 NOGO RECEPTOR ANTAGONISTS Biogen Idec MA Inc. (US) 2008-10-22 — — EP disclosed
US-20080219979-A1 Using cytokine receptor specific immunoglobulin as therapeutic tool in treatment and prevention of inflammatory, nervous system, skin and autoimmune disorders AMGEN INC. (US) 2008-09-11 — — US disclosed
US-20080220479-A1 Expression vector comprising nucleotide sequences coding cytokine receptor specific immunoglobulin for treatment and prevention of inflammation, cartilage degradation and bone resorption AMGEN, INC. (US) 2008-09-11 — — US disclosed
US-7422847-B2 Human E3α ubiquitin ligase family AMGEN INC. (US) 2008-09-09 — — US disclosed
WO-2008098019-A2 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS CARBYLAN BIOSURGERY, INC. (US) 2008-08-14 — — WO disclosed
WO-2008054603-A9 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC (US) 2008-07-03 — — WO disclosed
CN-101203250-A Methods and compositions for the delivery of biologically active agents INTERFACE BIOLOGICS INC (CA) 2008-06-18 — — CN disclosed
EP-1750764-A4 ANTIBODIES OF ANGIOGENESIS INHIBITING DOMAINS OF CD148 AMGEN INC (US) 2008-05-28 — — EP disclosed
WO-2008054603-A2 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS AMGEN INC. (US) 2008-05-08 — — WO disclosed
WO-2008053362-A2 BIORESPONSIVE POLYMERS INTERFACE BIOLOGICS, INC. (CA) 2008-05-08 — — WO disclosed
CN-100376291-C Porous drug matrices and methods of manufacture thereof ACUSPHERE INC (US) 2008-03-26 — — CN disclosed
CN-101124246-A Antibodies to the angiogenesis inhibitory domain of CD148 AMGEN INC (US) 2008-02-13 — — CN disclosed
EP-1240327-B1 INTERFERON-LIKE MOLECULES AND USES THEREOF AMGEN INC (US) 2008-02-06 — — EP disclosed
WO-2007148230-A2 GRAFTED POLYMERS AND USES THEREOF INTERFACE BIOLOGICS INCORPORATED (CA) 2007-12-27 — — WO disclosed
EP-1868664-A2 METHODS AND COMPOSITIONS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE AGENTS Interface Biologics Inc. (CA) 2007-12-26 — — EP disclosed
WO-2007114881-A1 TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES NEXBIO, INC. (US) 2007-10-11 — — WO disclosed
US-20070231831-A1 The human E3alpha ubiquitin ligase family AMGEN INC. (US) 2007-10-04 — — US disclosed
US-20070231264-A1 MAMMALIAN CYTOKINE; RELATED REAGENTS SCHERING CORPORATION (US) 2007-10-04 — — US disclosed
EP-1051972-B1 Nitric oxide donor composition and method for treatment of anal disorders STRAKAN INT LTD (GB) 2007-10-03 — — EP disclosed
US-20070225221-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-09-27 — — US disclosed
WO-2007103448-A2 RIFAXIMIN ANTI-RECTAL DYSFUNCTION PREPARATION SALIX PHARMACEUTICALS, INC. (US) 2007-09-13 — — WO disclosed
WO-2007095583-A2 METHODS FOR TREATING CANCER AND SENSITIZING CANCER CELLS USING THE SERINE PROTEASE INHIBITOR, MASPIN CHILDREN'S MEMORIAL RESEARCH CENTER (US) 2007-08-23 — — WO disclosed
US-20070190163-A1 Technology for preparation of macromolecular microspheres THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTE OF HEALTH 2007-08-16 — — US disclosed
WO-2007089601-A2 NOGO RECEPTOR ANTAGONISTS BIOGEN IDEC MA INC. (US) 2007-08-09 — — WO disclosed
EP-1814914-A2 ANTIBODIES THAT BIND UROKINASE-TYPE PLASMINOGEN ACTIVATOR AND EPITOPES THEREFOR The Regents of the University of Colorado (US) 2007-08-08 — — EP disclosed
CN-101005828-A Compositions comprising a mucoadhesive protein and an activeprinciple for mucosal delivery of said agents VIRUN INC (US) 2007-07-25 — — CN disclosed
EP-1807033-A2 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. (US) 2007-07-18 — — EP disclosed
EP-1805219-A1 ANGIOPOIETIN-2 SPECIFIC BINDING AGENTS Amgen, Inc (US) 2007-07-11 — — EP disclosed
US-7241438-B2 AK155 polypeptides SCHERING CORPORATION (US) 2007-07-10 — — US disclosed
US-20070141089-A1 Topical composition comprising terbinaf ine adn hydrocortisone LARNIER CATHERINE 2007-06-21 — — US disclosed
EP-0914431-B1 TRUNCATED SOLUBLE TUMOR NECROSIS FACTOR TYPE-I RECEPTORS AMGEN INC (US) 2007-06-13 — — EP disclosed
US-20070123459-A1 IL-17 like molecules and uses thereof AMGEN INC. (US) 2007-05-31 — — US disclosed
US-7220547-B2 Human E3α ubiquitin ligase family AMGEN, INC. (US) 2007-05-22 — — US disclosed
WO-2007052308-A2 GLYCO-PHOSPHORYLATED BIOLOGICALLY ACTIVE AGENTS BRAIN N' BEYOND BIOTECH PVT. LTD. (IN) 2007-05-10 — — WO disclosed
US-20070093418-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-04-26 — — US disclosed
US-20070093419-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-04-26 — — US disclosed
EP-1777234-A2 Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 Amgen Inc. (US) 2007-04-25 — — EP disclosed
US-7205275-B2 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. (US) 2007-04-17 — — US disclosed
EP-1768647-A1 COMPOSITIONS COMPRISING A MUCOADHESIVE PROTEIN AND AN ACTIVE PRINCIPLE FOR MUCOSAL DELIVERY OF SAID AGENT Virun, Inc. (US) 2007-04-04 — — EP disclosed
US-20070072801-A1 Administering peptibodies, i.e., peptides fused to other molecules such as an Fc domain of an antibody, where the peptide moiety specifically binds to Ang-2 ( angiopoietin-2); antiinflammatory agent; antirheumatic agent AMGEN INC. (US) 2007-03-29 — — US disclosed
EP-1767544-A2 Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 Amgen Inc. (US) 2007-03-28 — — EP disclosed
US-20070065868-A1 IL-17 receptor like molecules and uses thereof AMGEN INC. (US) 2007-03-22 — — US disclosed
EP-1764370-A2 Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 Amgen Inc. (US) 2007-03-21 — — EP disclosed
US-7189761-B2 Nitric oxide donor composition and method for treatment of anal disorders CELLEGY PHARMACEUTICALS, INC. 2007-03-13 — — US disclosed
US-7179625-B2 Human E3α ubiquitin ligase family AMGEN INC. (US) 2007-02-20 — — US disclosed
US-20070037891-A1 Methods and compositions for the delivery of biologically active agents INTERFACE BIOLOGICS (CA) 2007-02-15 — — US disclosed
EP-1750764-A2 ANTIBODIES OF ANGIOGENESIS INHIBITING DOMAINS OF CD148 Amgen Inc. (US) 2007-02-14 — — EP disclosed
WO-2007011290-A1 Bronchorelaxing agents based on indol- and isoquinoline derivatives RESPIRATORIUS AB (SE) 2007-01-25 — — WO disclosed
US-20070015219-A1 TNF receptor-like molecules and uses thereof AMGEN INC. 2007-01-18 — — US disclosed
WO-2007004067-A2 METHODS AND COMPOSITIONS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE AGENTS INTERFACE BIOLOGICS INC. (CA) 2007-01-11 — — WO disclosed
EP-1740187-A1 MACULAR EDEMA PATIENT SELECTION METHOD AND TREATMENT WITH EYE IMPLANT COMPRISING A STEROID Bausch & Lomb Incorporated (US) 2007-01-10 — — EP disclosed
US-7153669-B2 Nucleic acids encoding MK61 receptors AMGEN INC. (US) 2006-12-26 — — US disclosed
US-20060280774-A1 Compositions and methods for treating glaucoma ALLERGAN, INC. (US) 2006-12-14 — — US disclosed
EP-1727520-A2 METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS MEDCRYSTALFORMS, LLC (US) 2006-12-06 — — EP disclosed
EP-1562627-A4 CORTICOSTEROID CONJUGATES AND USES THEREOF MCLEAN HOSPITAL CORP (US) 2006-11-02 — — EP disclosed
US-7122198-B1 Fast dissolving composition with prolonged sweet taste PANACEA BIOTEC LIMITED (IN) 2006-10-17 — — US disclosed
EP-1708999-A1 BRONCHORELAXING COMPOUNDS RESPIRATORIUS AB (SE) 2006-10-11 — — EP disclosed
CN-1823737-A Porous drug matrices and methods of manufacture thereof ACUSPHERE INC (US) 2006-08-30 — — CN disclosed
US-7094566-B2 IL-17 receptor like molecules and uses thereof AMGEN INC., (US) 2006-08-22 — — US disclosed
EP-1656125-A2 TOPICAL COMPOSITION COMPRISING TERBINAFINE AND HYDROCORTISONE Novartis Consumer Health S.A. (CH) 2006-05-17 — — EP disclosed
WO-2006050177-A2 ANTIBODIES THAT BIND UROKINASE-TYPE PLASMINOGEN ACTIVATOR AND EPITOPES THEREFOR THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2006-05-11 — — WO disclosed
WO-2006045049-A1 ANGIOPOIETIN-2 SPECIFIC BINDING AGENTS AMGEN INC. (US) 2006-04-27 — — WO disclosed
WO-2006044206-A2 TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING NOVEN PHARMACEUTICALS, INC. (US) 2006-04-27 — — WO disclosed
US-20060078933-A1 IL-receptor like molecules and uses thereof AMGEN INC. (US) 2006-04-13 — — US disclosed
US-20060078966-A1 IL-17 receptor like polypeptides and uses thereof AMGEN INC. (US) 2006-04-13 — — US disclosed
US-20060078967-A1 Antibodies for IL-17 receptor like polypeptides and uses thereof AMGEN INC. (US) 2006-04-13 — — US disclosed
US-20060078604-A1 Transdermal drug delivery device including an occlusive backing NOVEN PHARMACEUTICALS, INC. 2006-04-13 — — US disclosed
US-7026360-B1 Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients INPHARMA S.A. (CH) 2006-04-11 — — US disclosed
EP-1637164-A2 Improved formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents Allergan, Inc. (US) 2006-03-22 — — EP disclosed
US-20060040919-A1 Bronchorelaxing compounds RESPIRATORIUS AB (SE) 2006-02-23 — — US disclosed
US-20060034846-A1 Use of TF antagonists NOVO NORDISK A/S (DK) 2006-02-16 — — US disclosed
CN-1240373-C Porous drug matrices and methods of making same ACUSPHERE INC (US) 2006-02-08 — — CN disclosed
US-20060024795-A1 Interferon-Like molecules and uses thereof WELCHER ANDREW 2006-02-02 — — US disclosed
US-20060024267-A1 TNFr/OPG-like molecules and uses thereof WELCHER ANDREW A 2006-02-02 — — US disclosed
US-20060018909-A1 Angiopoietin-2 specific binding agents AMGEN INC. 2006-01-26 — — US disclosed
WO-2006009825-A1 COMPOSITIONS COMPRISING A MUCOADHESIVE PROTEIN AND AN ACTIVE PRINCIPLE FOR MUCOSAL DELIVERY OF SAID AGENTS VIRUN, INC. (US) 2006-01-26 — — WO disclosed
US-6989147-B2 Truncated soluble tumor necrosis factor type-I and type-II receptors AMGEN INC. (US) 2006-01-24 — — US disclosed
EP-1615952-A2 METHODS OF TREATMENT OF INFLAMMATORY DISEASES USING SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 Amgen Inc. (US) 2006-01-18 — — EP disclosed
EP-0831912-B1 IMPROVED FORMULATION FOR CONTROLLED RELEASE OF DRUGS BY COMBINING HYDROPHILIC AND HYDROPHOBIC AGENTS ALLERGAN INC (US) 2006-01-11 — — EP disclosed
US-20060002931-A1 Antibodies of angiogenesis inhibiting domains CD148 AMGEN INC. (US) 2006-01-05 — — US disclosed
EP-1021204-B1 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMA (US) 2005-12-28 — — EP disclosed
US-20050281772-A1 Compositions for mucosal delivery of agents VIRUN, INC. 2005-12-22 — — US disclosed
WO-2005117970-A2 ANTIBODIES OF ANGIOGENESIS INHIBITING DOMAINS OF CD148 AMGEN, INC. (US) 2005-12-15 — — WO disclosed
US-20050250696-A1 Truncated soluble tumor necrosis factor type-I and type-II receptors FISHER ERIC F 2005-11-10 — — US disclosed
WO-2005099717-A1 MACULAR EDEMA PATIENT SELECTION METHOD AND TREATMENT WITH EYE IMPLANT COMPRISING A STEROID BAUSCH & LOMB INCORPORATED (US) 2005-10-27 — — WO disclosed
US-20050234221-A1 IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF AMGEN INC., A DELAWARE CORP. 2005-10-20 — — US disclosed
US-20050226814-A1 Diagnostic method and kit for implantation of a sustained release drug-delivery implant with a steroid BAUSCH & LOMB INCORPORATED 2005-10-13 — — US disclosed
US-20050221344-A1 Interferon-Like molecules and uses thereof WELCHER ANDREW 2005-10-06 — — US disclosed
US-20050181041-A1 Method of preparation of mixed phase co-crystals with active agents MEDCRYSTALFORMS, LLC (US) 2005-08-18 — — US disclosed
EP-1562627-A2 CORTICOSTEROID CONJUGATES AND USES THEREOF The McLean Hospital Corporation (US) 2005-08-17 — — EP disclosed
WO-2005070887-A1 BRONCHORELAXING COMPOUNDS RESPIRATORIUS AB (SE) 2005-08-04 — — WO disclosed
WO-2005055983-A2 METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS MEDCRYSTALFORMS, LLC (US) 2005-06-23 — — WO disclosed
US-20050123512-A1 Nucleic encoding interleukin-1 receptor antagonist-like proteins and uses thereof AMGEN, INC., A CORPORATION OF THE STATE OF DELAWARE 2005-06-09 — — US disclosed
US-20050089876-A1 Human E3alpha ubiquitin ligase family HAN HUI-QUAN (US) 2005-04-28 — — US disclosed
US-20050075391-A1 Nitric oxide donor composition and method for treatment of anal disorders CELLEGY PHARMACEUTICALS, INC. (US) 2005-04-07 — — US disclosed
US-20050074427-A1 IL-17 like molecules and uses thereof MEDLOCK EUGENE (US) 2005-04-07 — — US disclosed
US-20050048029-A1 Il-17 like molecules and uses thereof AMGEN, INC. (US) 2005-03-03 — — US disclosed
WO-2005013955-A2 TOPICAL COMPOSITION COMPRISING TERBINAFINE AND HYDROCORTISONE NOVARTIS CONSUMER HEALTH S.A. (CH) 2005-02-17 — — WO disclosed
US-20050009106-A1 Mammalian cytokine; related reagents SCHERING CORPORATION, A NEW JERSEY CORPORATION 2005-01-13 — — US disclosed
US-20050003451-A1 IL-17 like molecules and uses thereof MEDLOCK EUGENE (US) 2005-01-06 — — US disclosed
CN-1178699-C Pharmaceutical Compsns. contg. compounds with activity for enhancement of absorption of active ingredients — 2004-12-08 — — CN disclosed
EP-1477187-A1 Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents Allergan, Inc. (US) 2004-11-17 — — EP disclosed
WO-2004092215-A2 METHODS OF TREATMENT OF INFLAMMATORY DISEASES USING SPECIFIC BINDING AGENTS OF HUMAN ANGIOPOIETIN-2 AMGEN INC. (US) 2004-10-28 — — WO disclosed
US-20040208872-A1 Nucleic encoding interleukin-1 receptor antagonist-like proteins and uses thereof AMGEN, INC., A CORPORATION OF THE STATE OF DELAWARE 2004-10-21 — — US disclosed
US-6797813-B2 NUCLEOTIDE SEQUENCES CODING POLYPEPTIDES FOR USE IN THE TREATMENT OF RHEUMATIC AND RHEUMATOID ARTHRITIS SCHERING CORPORATION 2004-09-28 — — US disclosed
US-20040185037-A1 Human E3alpha ubiquitin ligase family HAN HUI-QUAN (US) 2004-09-23 — — US disclosed
EP-1456378-A2 IL-17 LIKE MOLECULES AND USES THEREOF Amgen Inc. (US) 2004-09-15 — — EP disclosed
US-20040157810-A1 Corticosteroid conjugates and uses thereof MCLEAN HOSPITAL CORPORATION, THE 2004-08-12 — — US disclosed
US-6733753-B2 ANTIINFLAMMATORY PROTEIN AMGEN INC. 2004-05-11 — — US disclosed
US-6706505-B1 ISOLATED NUCLEIC ACID MOLECULE COMPRISING SPECIFIED NUCLEOTIDE SEQUENCE, NUCLEOTIDE SEQUENCE ENCODING SPECIFIED POLYPEPTIDE, OR NUCLEOTIDE SEQUENCE FULLY COMPLEMENTARY TO EITHER AMGEN INC 2004-03-16 — — US disclosed
US-20040047863-A1 Combination therapy using a TNF binding protein for treating TNF-mediated diseases AMGEN INC. 2004-03-11 — — US disclosed
US-20040048799-A1 Combination therapy using a TNF binding protein for treating TNF-mediated diseases AMGEN INC. 2004-03-11 — — US disclosed
US-20040048338-A1 IL-17 receptor like molecules and uses thereof JING SHUQIAN (US) 2004-03-11 — — US disclosed
US-20040044001-A1 Use of II-1 inhibitors for treating II-1 mediated diseases AMGEN INC. 2004-03-04 — — US disclosed
WO-2004017904-A2 CORTICOSTEROID CONJUGATES AND USES THEREOF THE MCLEAN HOSPITAL CORPORATION (US) 2004-03-04 — — WO disclosed
US-20040023335-A1 IL-17 like molecules and uses thereof JING SHUQIAN (US) 2004-02-05 — — US disclosed
US-20040018241-A1 Bioadhesive compositions and methods for topical administration of active agents NOVEN PHARMACEUTICALS, INC. 2004-01-29 — — US disclosed
US-20030236193-A1 Methods of treatment using specific binding agents of human angiopoietin-2 AMGEN INC. 2003-12-25 — — US disclosed
US-6638528-B1 Pressure-sensitive adhesive matrix comprising blend of polyacrylate, polysiloxane, polyisobutylene, polyisoprene, polyamide or polystyrene; and insoluble, non-adhesive ethyl cellulose; polyvinylpyrrolidone crystallization inhibitor NOVEN PHARMACEUTICALS, INC. 2003-10-28 — — US disclosed
EP-1352656-A2 Combination therapy using a TNF binding protein for treating TNF-mediated diseases Amgen Inc. (US) 2003-10-15 — — EP disclosed
CN-1121854-C Transdermal device containing polyvinylpyrrolidone as solubility ehancer NOVEN PHARMA (US) 2003-09-24 — — CN disclosed
US-20030166069-A1 Interleukin-1 receptor antagonist-like molecules and uses thereof AMGEN, INC. 2003-09-04 — — US disclosed
US-20030166164-A1 IL-17 like molecules and uses thereof AMGEN INC. 2003-09-04 — — US disclosed
EP-1329225-A2 Transdermal device containing polyvinylpyrrolidone as solubility enhancer NOVEN PHARMACEUTICALS, INC. (US) 2003-07-23 — — EP disclosed
WO-2003055980-A2 IL-17 LIKE MOLECULES AND USES THEREOF AMGEN INC. (US) 2003-07-10 — — WO disclosed
US-20030124092-A1 IL-17 like molecules and uses thereoflike molecules and uses thereof AMGEN INC. 2003-07-03 — — US disclosed
EP-1317536-A2 TNF RECEPTOR-LIKE MOLECULES AND USES THEREOF Amgen Inc. (US) 2003-06-11 — — EP disclosed
US-20030099980-A1 IL-17 receptor like molecules and uses thereof JING SHUQIAN (US) 2003-05-29 — — US disclosed
US-6562363-B1 Bioadhesive compositions and methods for topical administration of active agents NOVEN PHARMACEUTICALS, INC. 2003-05-13 — — US disclosed
CN-1107499-C Nitric oxide donor compositions and methods for treating anal disorders NEPTUNE PHARMACEUTICAL CORP (US) 2003-05-07 — — CN disclosed
US-20030077246-A1 TNFr/OPG-like molecules and uses thereof WELCHER ANDREW A (US) 2003-04-24 — — US disclosed
US-20030072756-A1 Combination therapy using an IL-1 inhibitor and methotrexate AMGEN INC. 2003-04-17 — — US disclosed
US-20030073199-A1 Mammalian cytokine; related reagents SCHERING CORPORATION 2003-04-17 — — US disclosed
EP-1294765-A2 IL-17 MOLECULES AND USES THEREOF Amgen, Inc. (US) 2003-03-26 — — EP disclosed
US-20030054439-A1 Truncated soluble tumor necrosis factor type-I and type-II receptors AMGEN INC. 2003-03-20 — — US disclosed
US-20030004106-A1 Interleukin-1 receptor antagonist-related molecules and uses thereof AMGEN, INC., A CORPORATION OF THE STATE OF DELAWARE 2003-01-02 — — US disclosed
WO-2001068859-A9 IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF AMGEN INC (US) 2002-12-19 — — WO disclosed
EP-1266002-A2 IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF Amgen Inc., (US) 2002-12-18 — — EP disclosed
EP-1255837-A2 IL-17 LIKE MOLECULES AND USES THEREOF Amgen Inc. (US) 2002-11-13 — — EP disclosed
US-20020161042-A1 Nitric oxide donor composition and method for treatment of anal disorders CELLEGY PHARMACEUTICALS, INC. 2002-10-31 — — US disclosed
US-20020150977-A1 TNF receptor-like molecules and uses thereof AMGEN INC. 2002-10-17 — — US disclosed
EP-1246844-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-RELATED MOLECULES AND USES THEREOF Amgen Inc., (US) 2002-10-09 — — EP disclosed
US-20020137137-A1 Interferon-like molecules and uses thereof AMGEN, INC. 2002-09-26 — — US disclosed
WO-2002072107-A1 TOPICAL COMPOSITION CONTAINING HYDROCORTISONE NOVARTIS CONSUMER HEALTH S.A. (CH) 2002-09-19 — — WO disclosed
EP-1239870-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE MOLECULES AND USES THEREOF Amgen Inc., (US) 2002-09-18 — — EP disclosed
EP-1240197-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE MOLECULES AND USES THEREOF Amgen Inc., (US) 2002-09-18 — — EP disclosed
EP-1240327-A2 INTERFERON-LIKE MOLECULES AND USES THEREOF Amgen Inc., (US) 2002-09-18 — — EP disclosed
EP-1238077-A1 TNFR/OPG-LIKE MOLECULES AND USES THEREOF Amgen Inc., (US) 2002-09-11 — — EP disclosed
EP-1235561-A2 FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE Panacea Biotec Limited (IN) 2002-09-04 — — EP disclosed
US-20020119924-A1 Combination therapy using a TNF binding protein for treating TNF-mediated diseases AMGEN INC. 2002-08-29 — — US disclosed
CN-1365274-A Porous drug matrices and methods of making same ACUSPHERE INC (US) 2002-08-21 — — CN disclosed
US-20020049188-A1 Nitroglycerin ointment for treatment of pain associated with anal disease CELLEGY PHARMACEUTICALS, INC. 2002-04-25 — — US disclosed
US-20020045213-A1 IL-17 receptor like molecules and uses thereof AMGEN INC., A DELAWARE CORPORATION 2002-04-18 — — US disclosed
US-6369116-B1 SUSTAINED RELEASE DEXAMETHASON OCULEX PHARMACEUTICALS, INC. 2002-04-09 — — US disclosed
US-20020037524-A1 IL-17 like molecules and uses thereof AMGEN INC., A DELAWARE CORPORATION 2002-03-28 — — US disclosed
WO-2002020762-A2 TNF RECEPTOR-LIKE MOLECULES AND USES THEREOF AMGEN INC. (US) 2002-03-14 — — WO disclosed
WO-2002008285-A2 IL-17 MOLECULES AND USES THEREOF AMGEN, INC. (US) 2002-01-31 — — WO disclosed
US-20020009454-A1 Composition and method for treating inflammatory diseases AMGEN INC. 2002-01-24 — — US disclosed
US-20020004065-A1 Compositions and methods to effect the release profile in the transdermal administration of active agents KANIOS DAVID (US) 2002-01-10 — — US disclosed
US-6306820-B1 FAS ANTIGEN; RHEUMATIC DISEASES, ANTIINFLAMMATORY AGENTS; SEPTIC SHOCK PREVENTION AMGEN INC. 2001-10-23 — — US disclosed
US-20010025057-A1 Nitric oxide donor composition and method for treatment of anal disorders CELLEGY PHARMACEUTICALS, INC. 2001-09-27 — — US disclosed
US-6294170-B1 PROTEINACEOUS IL-1 INHIBITOR (INTERLEUKIN-1RA) BY EXTENDED DELIVERY MEANS, E.G., CONTROLLED RELEASE POLYMER FORMULATIONS (HYALURONAN), IL-1RA FUSION PROTEINS AND CHEMICAL ATTACHMENT, AND CONTINUOUS PUMP INFUSION, ARTHRITIS, FUSION PROTEIN AMGEN INC. 2001-09-25 — — US disclosed
WO-2001068859-A2 IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF AMGEN INC. (US) 2001-09-20 — — WO disclosed
WO-2001059120-A2 IL-17 LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-08-16 — — WO disclosed
WO-2001044472-A1 TNFR/OPG-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-21 — — WO disclosed
WO-2001043735-A1 NITROGLYCERIN OINTMENT FOR TREATMENT OF PAIN ASSOCIATED WITH ANAL DISEASE CELLEGY PHARMACEUTICALS, INC. (US) 2001-06-21 — — WO disclosed
WO-2001042304-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-RELATED MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 — — WO disclosed
WO-2001042305-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 — — WO disclosed
WO-2001041792-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 — — WO disclosed
WO-2001042474-A2 INTERFERON-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 — — WO disclosed
WO-2001039749-A2 FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE PANACEA BIOTEC LIMITED (IN) 2001-06-07 — — WO disclosed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 — — CN disclosed
US-6221383-B1 BLEND OF AT LEAST TWO POLYMERS, OR AT LEAST ONE POLYMER AND A SOLUBLE POLYVINYLPYRROLIDONE, IN COMBINATION WITH A DRUG PROVIDES A PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR A TRANSDERMAL DRUG DELIVERY SYSTEM NOVEN PHARMACEUTICALS, INC. 2001-04-24 — — US disclosed
EP-1051972-A1 Nitric oxide donor composition and method for treatment of anal disorders Cellegy Pharmaceuticals, Inc (US) 2000-11-15 — — EP disclosed
EP-0719145-B1 NITRIC OXIDE DONOR COMPOSITION FOR TREATMENT OF ANAL DISORDERS CELLEGY PHARMA INC (US) 2000-09-06 — — EP disclosed
US-6096728-A Composition and method for treating inflammatory diseases AMGEN INC. (US) 2000-08-01 — — US disclosed
EP-1021204-A2 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 2000-07-26 — — EP disclosed
US-6024976-A TRANSDERMAL DRUG DELIVERY WITH PRESSURE SENSITIVE ADHESIVE COMPOSITION OF POLYVINYLPYRROLIDONE WITH DRUG IN MULTILAYER PATCH NOVEN PHARMACEUTICALS, INC. (US) 2000-02-15 — — US disclosed
CN-1240479-A Truncated soluble tumor necrosis factor type-I and type-II receptors AMGEN INC (US) 2000-01-05 — — CN disclosed
EP-0949931-A1 COMBINATION THERAPY USING AN IL-1 INHIBITOR FOR TREATING IL-1 MEDIATED DISEASES AMGEN INC. (US) 1999-10-20 — — EP disclosed
EP-0942740-A2 COMBINATION THERAPY USING A TNF BINDING PROTEIN FOR TREATING TNF-MEDIATED DISEASES AMGEN INC. (US) 1999-09-22 — — EP disclosed
EP-0914431-A2 TRUNCATED SOLUBLE TUMOR NECROSIS FACTOR TYPE-I AND TYPE-II RECEPTORS AMGEN INC. (US) 1999-05-12 — — EP disclosed
CN-1215340-A Composition comprising interleukin-1 inhibitor and controlled release polymer AMGEN BULDER INC (US) 1999-04-28 — — CN disclosed
WO-1999015210-A2 BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1999-04-01 — — WO disclosed
EP-0904112-A1 COMPOSITION COMPRISING INTERLEUKIN-1 INHIBITOR AND CONTROLLED RELEASE POLYMER Amgen Inc., (US) 1999-03-31 — — EP disclosed
EP-0786999-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1999-01-20 — — EP disclosed
EP-0719145-A4 NITRIC OXIDE DONOR COMPOSITION AND METHOD FOR TREATMENT OF ANAL DISORDERS CELLEGY PHARMA INC (US) 1999-01-20 — — EP disclosed
EP-0792371-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1998-12-30 — — EP disclosed
US-5837698-A DERIVATIVES OF BETA-METHASONE, DEXAMETHASONE, BUDESONIDE AND TRIAMCINOLOLE WITH NITRATE G. D. SEARLE & CO. (US) 1998-11-17 — — US disclosed
WO-1998024463-A2 COMBINATION THERAPY USING A TNF BINDING PROTEIN FOR TREATING TNF-MEDIATED DISEASES AMGEN INC. (US) 1998-06-11 — — WO disclosed
WO-1998024477-A1 COMBINATION THERAPY USING AN IL-1 INHIBITOR FOR TREATING IL-1 MEDIATED DISEASES AMGEN INC. (US) 1998-06-11 — — WO disclosed
EP-0759750-A4 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1998-05-27 — — EP disclosed
US-5719197-A DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 1998-02-17 — — US disclosed
WO-1998001555-A2 TRUNCATED SOLUBLE TUMOR NECROSIS FACTOR TYPE-I AND TYPE-II RECEPTORS AMGEN INC. (US) 1998-01-15 — — WO disclosed
US-5693676-A USING NITROGLYCERIN TO TREAT ANAL FISSURES OR ULCERS, HEMORRHOIDS, LEVATOR SPASMS NEPTUNE PHARMACEUTICAL CORPORATION (US) 1997-12-02 — — US disclosed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 — — EP disclosed
WO-1997028828-A1 COMPOSITION COMPRISING INTERLEUKIN-1 INHIBITOR AND CONTROLLED RELEASE POLYMER AMGEN BOULDER INC. (US) 1997-08-14 — — WO disclosed
US-5656286-A BLEND OF TWO POLYMERS; PRESSURE SENSITIVE ADHESIVE NOVEN PHARMACEUTICALS, INC. (US) 1997-08-12 — — US disclosed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 — — EP disclosed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 — — EP disclosed
CN-1143318-A Transdermal device containing polyvinylpyrrolidone as dissolution enhancer NOVEN PHARMA (US) 1997-02-19 — — CN disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 — — WO disclosed
WO-1996040086-A2 COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 — — WO disclosed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 — — CN disclosed
CN-1131392-A Nitric oxide donor composition and method for treatment of anal disorders NEPTUNE PHARMACEUTICAL CORP (US) 1996-09-18 — — CN disclosed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 — — US disclosed
EP-0719145-A1 NITRIC OXIDE DONOR COMPOSITION AND METHOD FOR TREATMENT OF ANAL DISORDERS NEPTUNE PHARMACEUTICAL CORPORATION (US) 1996-07-03 — — EP disclosed
CN-1125394-A Novel therapeutic drug delivery system IMARX PHARMACEUTICAL CORP (US) 1996-06-26 — — CN disclosed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 — — WO disclosed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 — — WO disclosed
WO-1995032715-A1 NITRIC OXIDE DONOR COMPOSITION AND METHOD FOR TREATMENT OF ANAL DISORDERS NEPTUNE PHARMACEUTICAL CORPORATION (US) 1995-12-07 — — WO disclosed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 — — WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 — — US disclosed
US-5183815-A Bone acting agents MERCK & CO., INC. (US) 1993-02-02 — — US disclosed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 — — EP disclosed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (42 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002278-A1 Pharmaceutical Compositions for Rectal Administration SI, CROCC, FABP2 HIF1A 2920/4885HSD17B10 775/4885NR3C1 2479/4885
US-20110166331-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS IL17A, IL23R, IL2RA HIF1A 646/4885HSD17B10 812/4885NR3C1 558/4885
US-20140227266-A1 NOGO Receptor Antagonists NGFR, RTN4, SRPRB HIF1A 4095/4885HSD17B10 4752/4885NR3C1 815/4885
US-20100041771-A1 Bioreponsive Polymers PEPD, PREP, DNPEP HIF1A 1886/4885HSD17B10 1213/4885NR3C1 4835/4885
US-20120308566-A1 USE OF IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS IL23R, IL15RA, IL2RA HIF1A 1951/4885HSD17B10 3022/4885NR3C1 1188/4885
US-20160159878-A1 NOGO Receptor Antagonists NGFR, RTN4, SRPRB HIF1A 4095/4885HSD17B10 4752/4885NR3C1 815/4885
US-20040044001-A1 Use of II-1 inhibitors for treating II-1 mediated diseases IL1A, IL1B, IL1R1 HIF1A 312/4885HSD17B10 3162/4885NR3C1 1109/4885
US-20100028345-A1 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS IL17A, IL23R, IL15RA HIF1A 1211/4885HSD17B10 2217/4885NR3C1 1158/4885
US-20040157810-A1 Corticosteroid conjugates and uses thereof NR3C1, NR3C2, C3AR1 HIF1A 4459/4885HSD17B10 237/4885NR3C1 1/4885
US-20100048520-A1 RIFAXIMIN ANTI-RECTAL DYSFUNCTION PREPARATION RDX, VIP, RXFP1 HIF1A 1848/4885HSD17B10 420/4885NR3C1 1019/4885
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US-10195311-B2 Local delivery of drugs from self assembled coatings OGFR, F7, F13B HIF1A 2180/4885HSD17B10 1857/4885NR3C1 2409/4885
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US-20100034862-A1 COVALENTLY GRAFTED PHARMACEUTICALLY ACTIVE POLYMERS TIE1, TEK, FLT1 HIF1A 593/4885HSD17B10 3307/4885NR3C1 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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