Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.64 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723217 | 0.85 | BRD4 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28477450 | 0.80 | ALDH1A1 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13020120 | 0.78 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4540682 | 0.78 | PDPK1 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29348731 | 0.78 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13332848 | 0.77 | SMN1; SMN2 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13020273 | 0.76 | HDAC3 (0.74) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13020114 | 0.75 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4437360 | 0.74 | BRD4 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14322593 | 0.74 | LMNA (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010140835-A2 | NOVEL PYRIDONE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR TREATING CANCER | 연세대학교 산학협력단 (KR) | 2010-12-09 | — | — | WO | disclosed |