Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975793 | 0.85 | MEN1 (0.46) | MEN1KMT2ATDP1LPAR2LPAR3 | |
| SCHEMBL499769 | 0.80 | MEN1 (0.38) | MEN1KMT2ATDP1LPAR2LPAR3 | |
| SCHEMBL6965382 | 0.77 | TDP1 (0.44) | MEN1KMT2ATDP1 | |
| SCHEMBL8055699 | 0.76 | MEN1 (0.35) | MEN1KMT2ATDP1LPAR2LPAR3 | |
| SCHEMBL11590408 | 0.74 | — | — | |
| SCHEMBL16637517 | 0.71 | — | — | |
| SCHEMBL10790063 | 0.71 | — | — | |
| SCHEMBL482317 | 0.71 | LPAR2 (0.37) | MEN1KMT2ATDP1LPAR2LPAR3 | |
| SCHEMBL11216760 | 0.70 | TDP1 (0.45) | MEN1KMT2ATDP1LPAR2LPAR3 | |
| SCHEMBL28016994 | 0.70 | MEN1 (0.31) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331397-A1 | 2-5A ANALOGS AND THEIR METHODS OF USE | ALIOS BIOPHARMA, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331397-A1 | 2-5A ANALOGS AND THEIR METHODS OF USE | RNASEL, RNASE1, RNASEH1 | MEN1 2972/4885KMT2A 1685/4885TDP1 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.