SCHEMBL13021185

SCHEMBL13021185

Cc1cc(O)c2c(C)c(C)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.46
SELL P14151 1/20 0.41
SELP P16109 1/20 0.41
SELE P16581 1/20 0.41
TRPA1 O75762 4/20 0.38
CYP1A2 P05177 5/20 0.37
CYP2A6 P11509 4/20 0.37
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ATM Q13315 1/20 0.37
TSHR P16473 2/20 0.34
CASP1 P29466 1/20 0.34
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13316749 0.79 TP53 (0.46) ACHESELLSELPSELETRPA1
SCHEMBL13021183 0.77 ACHE (0.48) ACHESELLSELPSELETRPA1
SCHEMBL6355906 0.77 SELL (0.48) ACHESELLSELPSELETRPA1
SCHEMBL14065775 0.76 ATM (0.35) ACHESELLSELPSELETRPA1
SCHEMBL29367799 0.75 SELL (0.46) ACHESELLSELPSELETRPA1
SCHEMBL28942916 0.75 CYP1A2 (0.45) ACHESELLSELPSELETRPA1
SCHEMBL18068457 0.75 SELL (0.46) ACHESELLSELPSELETRPA1
SCHEMBL5676514 0.74 SELL (0.55) ACHESELLSELPSELETRPA1
SCHEMBL5407973 0.72 TRPA1 (0.54) TRPA1CYP1A2CYP2A6TDP1ATM
SCHEMBL12800170 0.72 MEN1 (0.56) ACHESELLSELPSELETRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8308998-B2 Polarizing film, coating liquid, and image display NITTO DENKO CORPORATION (JP) 2012-11-13 US disclosed
US-20100288166-A1 POLARIZING FILM, COATING LIQUID, AND IMAGE DISPLAY NITTO DENKO CORPORATION (JP) 2010-11-18 US disclosed
US-7304091-B2 Statin-like compounds MYCO TEO A/S (DK) 2007-12-04 US disclosed