SCHEMBL5407973

SCHEMBL5407973

Cc1ccc2cccc(O)c2c1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.54
ATM Q13315 1/20 0.54
TSHR P16473 4/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
CYP3A4 P08684 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP1A2 P05177 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
CYP2A6 P11509 1/20 0.45
DNMT1 P26358 1/20 0.45
CACNA1B Q00975 1/20 0.45
APBA1 Q02410 1/20 0.45
MCL1 Q07820 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
METAP2 P50579 1/20 0.44
CDK2 P24941 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5950624 0.84 TRPA1 (0.50) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL29771813 0.84 TRPA1 (0.50) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL16800740 0.83 ALDH1A1 (0.48) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL6545340 0.83 ALDH1A1 (0.56) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL5950773 0.81 ALDH1A1 (0.56) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL12807356 0.80 TRPA1 (0.50) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL1402326 0.79 TRPA1 (0.54) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL25945835 0.79 ALDH1A1 (0.45) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL21315102 0.79 ALDH1A1 (0.42) TRPA1ATMTSHRALDH1A1HPGD
SCHEMBL29680527 0.79 ALDH1A1 (0.42) TRPA1ATMTSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153555-B1 PHOTOOXIDATION OF PHENOLIC COMPOUNDS DSM IP ASSETS BV (NL) 2024-01-31 EP disclosed
EP-4153555-A1 PHOTOOXIDATION OF PHENOLIC COMPOUNDS DSM IP Assets B.V. (NL) 2023-03-29 EP disclosed
CN-115667201-A Photooxidation of phenolic compounds 帝斯曼知识产权资产管理有限公司 2023-01-31 CN disclosed
WO-2021234080-A1 PHOTOOXIDATION OF PHENOLIC COMPOUNDS DSM IP ASSETS B.V. (NL) 2021-11-25 WO disclosed
US-7304091-B2 Statin-like compounds MYCO TEO A/S (DK) 2007-12-04 US disclosed
US-7304091-B2 Statin-like compounds MYCO TEO A/S (DK) 2007-12-04 US disclosed
US-20050228042-A1 Statin-like compounds NOVOZYMES A/S (DK) 2005-10-13 US disclosed
EP-1453819-A2 STATIN-LIKE COMPOUNDS Novozymes A/S (DK) 2004-09-08 EP disclosed
WO-2003048148-A9 STATIN-LIKE COMPOUNDS NOVOZYMES AS (DK) 2004-04-29 WO disclosed
WO-2003048148-A2 STATIN-LIKE COMPOUNDS NOVOZYMES A/S (DK) 2003-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050228042-A1 Statin-like compounds HMGCR, SREBF1, ACSL5 TRPA1 4263/4885ATM 4070/4885TSHR 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.