Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | STAT6 | P42226 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 7/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021233 | 0.87 | HIF1A (0.75) | HIF1ATP53STAT6PAX8 | |
| SCHEMBL2784937 | 0.87 | HIF1A (0.75) | HIF1ATP53STAT6PAX8 | |
| SCHEMBL2784929 | 0.87 | HIF1A (0.75) | HIF1ATP53STAT6PAX8 | |
| SCHEMBL13021321 | 0.87 | TP53 (0.57) | HIF1ATP53STAT6CASP6DNPH1 | |
| SCHEMBL2785112 | 0.86 | HIF1A (0.48) | HIF1ATP53STAT6PAX8CASP6 | |
| SCHEMBL2785116 | 0.86 | HIF1A (0.48) | HIF1ATP53STAT6PAX8CASP6 | |
| SCHEMBL25286647 | 0.80 | DNPH1 (0.71) | TP53DNPH1TAS1R3TAS1R1FBP1 | |
| SCHEMBL29494827 | 0.80 | DNPH1 (0.71) | TP53DNPH1TAS1R3TAS1R1FBP1 | |
| SCHEMBL2786833 | 0.75 | TP53 (0.48) | HIF1ATP53STAT6CASP6P2RY2 | |
| SCHEMBL2788446 | 0.75 | HIF1A (0.77) | HIF1ATP53STAT6PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | HAVCR2, EIF2AK2, OAT | HIF1A 247/4885TP53 2531/4885STAT6 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.