Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384918 | 0.96 | POLB (0.36) | POLBAPEX1HTTTDP1 | |
| SCHEMBL373843 | 0.89 | NPC1 (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL2238210 | 0.89 | POLB (0.33) | POLBAPEX1HTTTDP1 | |
| SCHEMBL29613654 | 0.89 | NPC1 (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL2778858 | 0.88 | POLB (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL29399534 | 0.88 | POLB (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL12128112 | 0.88 | GAA (0.33) | POLBAPEX1HTTTDP1 | |
| SCHEMBL21956086 | 0.86 | HTT (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL30965309 | 0.86 | HTT (0.35) | POLBAPEX1HTTTDP1 | |
| SCHEMBL8397404 | 0.85 | TDP1 (0.37) | POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825257-B1 | Synthesis of benzotriazole monomer | BAUSCH & LOMB INCORPORATED (US) | 2010-11-02 | — | — | US | disclosed |