SCHEMBL2238210

SCHEMBL2238210

C=C(C)C(=O)OCCOc1cc(-n2nc3ccc(C(C)(C)C)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613654 0.91 NPC1 (0.35) POLBAPEX1HTTTDP1
SCHEMBL373843 0.91 NPC1 (0.35) POLBAPEX1HTTTDP1
SCHEMBL29399534 0.90 POLB (0.35) POLBAPEX1HTTTDP1
SCHEMBL2778858 0.90 POLB (0.35) POLBAPEX1HTTTDP1
SCHEMBL15385236 0.89 POLB (0.35) POLBAPEX1HTTTDP1
SCHEMBL13021486 0.89 POLB (0.32) POLBAPEX1HTTTDP1
SCHEMBL30965309 0.88 HTT (0.35) POLBAPEX1HTTTDP1
SCHEMBL21956086 0.88 HTT (0.35) POLBAPEX1HTTTDP1
SCHEMBL8397404 0.86 TDP1 (0.37) POLBAPEX1HTTTDP1
SCHEMBL19252768 0.86 TDP1 (0.39) POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003222-B2 Resin composition for forming ultraviolet absorbing layer and laminate comprising ultraviolet absorbing layer NIPPON SHOKUBAI CO., LTD. (JP) 2011-08-23 US disclosed
US-20090110936-A1 Resin Composition for Forming Ultraviolet Absorbing Layer and Laminate Comprising Ultraviolet Absorbing Layer NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-30 US disclosed
EP-1036834-B1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL NIPPON CATALYTIC CHEM IND (JP) 2006-06-14 EP disclosed
US-6372355-B1 MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-16 US disclosed
EP-1036834-A1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL Nippon Shokubai Co., Ltd. (JP) 2000-09-20 EP disclosed