SCHEMBL13022121

SCHEMBL13022121

Cc1ccc2c(c1)C(=O)Oc1c(oc3ccc(C)cc13)N2c1ccccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.41
MAPT P10636 4/20 0.41
ALDH1A1 P00352 4/20 0.41
TP53 P04637 2/20 0.41
CYP3A4 P08684 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
MGLL Q99685 1/20 0.37
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
PRKDC P78527 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022830 0.94 KDM4E (0.42) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022132 0.88 KDM4E (0.48) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022128 0.86 MEN1 (0.48) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022159 0.85 KDM4E (0.39) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022062 0.85 MAPT (0.35) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13023912 0.84 LMNA (0.40) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022775 0.84 MAPT (0.36) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022846 0.83 KDM4E (0.50) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022138 0.82 TP53 (0.38) KDM4EMAPTALDH1A1TP53CYP3A4
SCHEMBL13022878 0.82 KDM4E (0.40) KDM4EMAPTALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 KDM4E 2852/4885MAPT 2367/4885ALDH1A1 579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.