SCHEMBL13023912

SCHEMBL13023912

Cc1ccc(N2c3ccccc3C(=O)Oc3c2oc2ccccc32)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
MAOB P27338 3/20 0.40
CASP3 P42574 1/20 0.38
KDM4E B2RXH2 4/20 0.38
POLB P06746 2/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 2/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAOA P21397 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
TNKS O95271 1/20 0.36
PARP1 P09874 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
PARP2 Q9UGN5 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023926 0.88 KDM4E (0.44) MAOBKDM4EPOLBALDH1A1MAPT
SCHEMBL13022830 0.88 KDM4E (0.42) LMNACASP3KDM4EPOLBALDH1A1
SCHEMBL13023954 0.87 PIK3CD (0.37) LMNAMAOBKDM4EPOLBTP53
SCHEMBL13023919 0.86 MEN1 (0.41) LMNAMAOBCASP3KDM4EALDH1A1
SCHEMBL13023835 0.85 LMNA (0.36) LMNAMAOBCASP3KDM4EPOLB
SCHEMBL13022121 0.84 KDM4E (0.41) LMNAKDM4EPOLBALDH1A1MAPT
SCHEMBL13022878 0.83 KDM4E (0.40) LMNAMAOBKDM4EPOLBALDH1A1
SCHEMBL13022846 0.82 KDM4E (0.50) MAOBKDM4EPOLBALDH1A1MAPT
SCHEMBL13023931 0.81 SMN1; SMN2 (0.32) LMNAKDM4EALDH1A1MAPTTP53
SCHEMBL13022132 0.80 KDM4E (0.48) MAOBKDM4EPOLBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 LMNA 1808/4885MAOB 1349/4885CASP3 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.