SCHEMBL13022124

SCHEMBL13022124

Cc1ccc2c(c1)COc1c(oc3ccc(C)cc13)N2c1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.35
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 3/20 0.33
PRKDC P78527 1/20 0.32
TP53 P04637 2/20 0.32
HPGD P15428 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RAB9A P51151 2/20 0.32
MITF O75030 1/20 0.32
PKM P14618 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022828 0.94 NPSR1 (0.36) MAPTALDH1A1NPSR1KDM4EPRKDC
SCHEMBL13022133 0.87 KDM4E (0.37) MAPTALDH1A1NPSR1KDM4ETP53
SCHEMBL13022127 0.87 MEN1 (0.43) MAPTALDH1A1KDM4ETP53HPGD
SCHEMBL13022142 0.85 TP53 (0.38) MAPTALDH1A1NPSR1KDM4ETP53
SCHEMBL13022163 0.85 PRKDC (0.33) PRKDCRAB9AMITFPKMNPC1
SCHEMBL13023913 0.84 LMNA (0.34) MAPTALDH1A1NPSR1KDM4ETP53
SCHEMBL13022877 0.83 NPSR1 (0.35) MAPTALDH1A1NPSR1KDM4EPRKDC
SCHEMBL13022860 0.81 TP53 (0.39) MAPTALDH1A1NPSR1KDM4ETP53
SCHEMBL13022067 0.81 MAPT (0.36) MAPTALDH1A1NPSR1KDM4EPRKDC
SCHEMBL13022162 0.81 PRKDC (0.31) PRKDCRAB9AMITFPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MAPT 2367/4885ALDH1A1 579/4885NPSR1 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.