SCHEMBL13023913

SCHEMBL13023913

Cc1ccc(N2c3ccccc3COc3c2oc2ccccc32)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
MAOB P27338 1/20 0.34
CASP3 P42574 1/20 0.33
MAPT P10636 5/20 0.32
RAB9A P51151 4/20 0.32
NPSR1 Q6W5P4 3/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
NPC1 O15118 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MPO P05164 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
POLB P06746 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023955 0.87 RAB9A (0.33) LMNAMAPTRAB9ANPSR1L3MBTL1
SCHEMBL13022828 0.87 NPSR1 (0.36) CASP3MAPTRAB9ANPSR1L3MBTL1
SCHEMBL13023920 0.87 LMNA (0.35) LMNAMAOBMAPTRAB9AL3MBTL1
SCHEMBL13023927 0.87 MAPT (0.35) MAOBCASP3MAPTRAB9ANPSR1
SCHEMBL13022124 0.84 MAPT (0.35) MAOBCASP3MAPTRAB9ANPSR1
SCHEMBL13022877 0.83 NPSR1 (0.35) CASP3MAPTRAB9ANPSR1NPC1
SCHEMBL13023934 0.82 NPC1 (0.33) MAPTRAB9ANPSR1L3MBTL1NPC1
SCHEMBL13022151 0.81 NPSR1 (0.33) MAOBMAPTRAB9ANPSR1L3MBTL1
SCHEMBL13023843 0.81 LMNA (0.36) LMNAMAOBCASP3MAPTRAB9A
SCHEMBL13023911 0.80 NPSR1 (0.40) LMNACASP3MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 LMNA 1808/4885MAOB 1349/4885CASP3 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.