SCHEMBL13023734

SCHEMBL13023734

Cc1cc(C)c(N2c3ccccc3S(=O)(=O)c3ccoc32)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
MAPT P10636 3/20 0.39
POLB P06746 3/20 0.39
TP53 P04637 2/20 0.39
RXFP1 Q9HBX9 1/20 0.33
MAOA P21397 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023683 0.86 LMNA (0.41) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13023743 0.85 POLB (0.41) LMNAMAPTPOLBTP53RXFP1
SCHEMBL2500153 0.84 LMNA (0.47) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13022722 0.82 MAPT (0.39) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13022534 0.78 LMNA (0.46) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13023676 0.77 POLB (0.45) LMNAMAPTPOLBTP53
SCHEMBL13023695 0.77 LMNA (0.38) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13023686 0.75 TP53 (0.36) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13023907 0.75 PIK3CD (0.34) LMNAMAPTPOLBTP53RXFP1
SCHEMBL13022813 0.73 LMNA (0.34) LMNAMAPTPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 LMNA 1808/4885MAPT 2367/4885POLB 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.