SCHEMBL13023765

SCHEMBL13023765

Cc1ccc(N2c3ccccc3COc3ccoc32)c(-c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALDH1A1 P00352 1/20 0.31
CYP19A1 P11511 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
NPY1R P25929 1/20 0.30
HTT P42858 1/20 0.30
NPY2R P49146 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023744 0.85 MAPT (0.36) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL13023370 0.84 MAPT (0.43) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL13023691 0.83 HTT (0.33) MAPTMEN1KMT2AHDAC7NPC1
SCHEMBL13023773 0.83 NPC1 (0.35) MAPTKMT2AALDH1A1HDAC7NPC1
SCHEMBL13023700 0.82 P2RX4 (0.35) MEN1KMT2ACYP1A2CYP2C9HDAC7
SCHEMBL13023769 0.81 HTT (0.36) MAPTMEN1KMT2AALDH1A1NPC1
SCHEMBL13023780 0.81 ALDH1A1 (0.35) MAPTMEN1KMT2ACYP1A2ALDH1A1
SCHEMBL13023775 0.80 MAOB (0.38) MAPTALDH1A1HDAC7HTT
SCHEMBL13022560 0.79 MAPT (0.41) MAPTMEN1KMT2ACYP1A2CYP2C9
SCHEMBL13023927 0.78 MAPT (0.35) MAPTMEN1KMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MAPT 2367/4885MEN1 725/4885KMT2A 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.