SCHEMBL13023780

SCHEMBL13023780

COc1cc(C)ccc1N1c2ccccc2COc2ccoc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
HTR1A P08908 2/20 0.34
HTR3A P46098 2/20 0.34
GRM1 Q13255 1/20 0.34
GRM4 Q14833 1/20 0.34
ADCY2 Q08462 1/20 0.34
GAA P10253 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SCN9A Q15858 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023816 0.87 MAPT (0.33) ALDH1A1MAPTLMNAGAAMEN1
SCHEMBL13023744 0.85 MAPT (0.36) ALDH1A1MAPTLMNAHTR1AHTR3A
SCHEMBL13023399 0.84 ALDH1A1 (0.40) ALDH1A1MAPTLMNAHTR1AHTR3A
SCHEMBL13023670 0.83 TUBB4A (0.38) ALDH1A1MAPTLMNAHTR1AHTR3A
SCHEMBL13023747 0.83 MEN1 (0.39) ALDH1A1MAPTLMNAHTR1AHTR3A
SCHEMBL13023672 0.82 ADCY2 (0.39) ALDH1A1MAPTLMNAHTR1AHTR3A
SCHEMBL13023765 0.81 MAPT (0.40) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL13023782 0.81 MEN1 (0.42) ALDH1A1MAPTLMNAGAAMEN1
SCHEMBL13022552 0.79 ALDH1A1 (0.45) ALDH1A1MAPTLMNAHTR1AGAA
SCHEMBL13023742 0.78 ADCY2 (0.43) ALDH1A1MAPTLMNAGRM1GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 ALDH1A1 579/4885MAPT 2367/4885LMNA 1808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.