SCHEMBL13023970

SCHEMBL13023970

Cc1cc(C)c(N2c3cccnc3Oc3ncccc32)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
MAPT P10636 3/20 0.35
POLB P06746 1/20 0.35
RAPGEF4 Q8WZA2 2/20 0.34
MYC P01106 1/20 0.33
GAA P10253 1/20 0.33
PSMD14 O00487 1/20 0.33
COPS5 Q92905 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024015 0.90 LMNA (0.35) LMNAMAPTPOLB
SCHEMBL13024000 0.90 LMNA (0.36) LMNAMAPTPOLBRAPGEF4GAA
SCHEMBL13024018 0.89 LMNA (0.34) LMNAMAPTPOLB
SCHEMBL13024017 0.86 LMNA (0.38) LMNAMAPTPOLB
SCHEMBL13023977 0.86 LMNA (0.41) LMNAMAPTPOLB
SCHEMBL13023988 0.85 LMNA (0.38) LMNAMAPTPOLBALDH1A1
SCHEMBL13022998 0.81 TRPV1 (0.32)
SCHEMBL13024004 0.81 LMNA (0.37) LMNAMAPTPOLB
SCHEMBL13024002 0.80 LMNA (0.37) LMNAMAPTPOLB
SCHEMBL13024026 0.80 LMNA (0.39) LMNAMAPTPOLBRAPGEF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 LMNA 1808/4885MAPT 2367/4885POLB 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.